ATXN1 - Wiki-MPM

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	RAI2	retinoic acid induced 2
Novel	RAPGEF1	Rap guanine nucleotide exchange factor 1	Frs2-mediated activation Frs2-mediated activation Downstream signal transduction MET activates RAP1 and RAC1 RAC3 GTPase cycle Erythropoietin activates RAS Erythropoietin activates RAS Regulation of signaling by CBL
Novel	RAPGEF4	Rap guanine nucleotide exchange factor 4	Integrin signaling Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Rap1 signalling Regulation of insulin secretion
Novel	RBFOX1	RNA binding fox-1 homolog 1	MECP2 regulates transcription factors
Novel	RBFOX2	RNA binding fox-1 homolog 2	FGFR2 alternative splicing
Novel	RBM26	RNA binding motif protein 26	Nuclear RNA decay
Novel	RBPMS	RNA binding protein, mRNA processing factor
Novel	RCC1L	RCC1 like	rRNA modification in the mitochondrion Mitochondrial mRNA modification
Novel	RCN1	reticulocalbin 1	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Novel	REL	REL proto-oncogene, NF-kB subunit	Activation of NF-kappaB in B cells		Hodgkin lymphoma
Novel	RHOXF2	Rhox homeobox family member 2
Novel	RNF10	ring finger protein 10
Novel	RNF31	ring finger protein 31	TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway
Novel	RNF4	ring finger protein 4	Processing of DNA double-strand break ends Antigen processing: Ubiquitination & Proteasome degradation
Novel	RPL19	ribosomal protein L19	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	(S)-3-phenyllactic acid Anisomycin Puromycin
Novel	SAR1A	secretion associated Ras related GTPase 1A
Novel	SEMA4G	semaphorin 4G
Novel	SETD2	SET domain containing 2, histone lysine methyltransferase	PKMTs methylate histone lysines
Novel	SETD6	SET domain containing 6, protein lysine methyltransferase	PKMTs methylate histone lysines
Novel	SF1	splicing factor 1	mRNA Splicing - Major Pathway	Artenimol

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