Search Results for: APP

2116 interactions involving APP - amyloid beta precursor protein found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
UNG uracil DNA glycosylase
  • 4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID
  • 1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE
  • 3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid
  • Hyper IgM syndromes, autosomal recessive type, including the following three diseases: Activation-induced cytidine deaminase (AICD) defect; Uracil nucleotide glycoside glycosylase (UNG) defect; Immunodeficiency with hyper-IgM type 3
UPF3A UPF3A regulator of nonsense mediated mRNA decay
  • Regulation of expression of SLITs and ROBOs
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
URI1 URI1 prefoldin like chaperone
USE1 unconventional SNARE in the ER 1
  • COPI-dependent Golgi-to-ER retrograde traffic
USF1 upstream transcription factor 1
  • Estrogen-dependent gene expression
  • Regulation of MITF-M-dependent genes involved in pigmentation
  • Familial combined hyperlipidemia (FCHL)
USP12 ubiquitin specific peptidase 12
  • Ub-specific processing proteases
USP2 ubiquitin specific peptidase 2
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • Ub-specific processing proteases
  • Regulation of TP53 Degradation
USP39 ubiquitin specific peptidase 39
  • mRNA Splicing - Major Pathway
USP5 ubiquitin specific peptidase 5
  • Ub-specific processing proteases
  • Synthesis of active ubiquitin: roles of E1 and E2 enzymes
USP6 ubiquitin specific peptidase 6
USP6NL USP6 N-terminal like
  • Retrograde transport at the Trans-Golgi-Network
UTP14A UTP14A small subunit processome component
  • rRNA modification in the nucleus and cytosol
  • Major pathway of rRNA processing in the nucleolus and cytosol
UTP23 UTP23 small subunit processome component
UTP25 UTP25 small subunit processome component
  • rRNA modification in the nucleus and cytosol
  • Major pathway of rRNA processing in the nucleolus and cytosol
UTP4 UTP4 small subunit processome component
  • rRNA modification in the nucleus and cytosol
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Familial cholestasis, including: Progressive familial intrahepatic cholestasis (PFIC); Benign recurrent intrahepatic cholestasis (BRIC); Intrahepatic cholestasis of pregnancy (ICP); North American Indian childhood cirrhosis (NAIC)
UXT ubiquitously expressed prefoldin like chaperone
  • Transcriptional Regulation by E2F6
VAC14 VAC14 component of PIKFYVE complex
  • Synthesis of PIPs at the Golgi membrane
  • Synthesis of PIPs at the Golgi membrane
  • Synthesis of PIPs at the early endosome membrane
  • Synthesis of PIPs at the early endosome membrane
  • Synthesis of PIPs at the late endosome membrane
  • Synthesis of PIPs at the late endosome membrane
VAMP3 vesicle associated membrane protein 3
  • ER-Phagosome pathway
  • Retrograde transport at the Trans-Golgi-Network
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
  • RHOA GTPase cycle
  • RHOB GTPase cycle
  • RHOC GTPase cycle
  • CDC42 GTPase cycle
  • RAC1 GTPase cycle
  • RAC2 GTPase cycle
  • RHOD GTPase cycle
  • RHOQ GTPase cycle
  • RHOH GTPase cycle
  • RHOG GTPase cycle
  • RHOJ GTPase cycle
  • RAC3 GTPase cycle
  • RHOF GTPase cycle
VASH2 vasohibin 2
  • Carboxyterminal post-translational modifications of tubulin
VAT1L vesicle amine transport 1 like

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