Search Results for: AR

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel RBAK RB associated KRAB zinc finger
Novel RCHY1 ring finger and CHY zinc finger domain containing 1
  • Translesion Synthesis by POLH
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Novel REL REL proto-oncogene, NF-kB subunit
  • Activation of NF-kappaB in B cells
  • Hodgkin lymphoma
Novel RELA RELA proto-oncogene, NF-kB subunit
  • Activation of NF-kappaB in B cells
  • RIP-mediated NFkB activation via ZBP1
  • Regulated proteolysis of p75NTR
  • Downstream TCR signaling
  • NF-kB is activated and signals survival
  • Senescence-Associated Secretory Phenotype (SASP)
  • FCERI mediated NF-kB activation
  • DEx/H-box helicases activate type I IFN and inflammatory cytokines production
  • PKMTs methylate histone lysines
  • Transcriptional regulation of white adipocyte differentiation
  • TAK1-dependent IKK and NF-kappa-B activation
  • Interleukin-1 processing
  • SUMOylation of immune response proteins
  • IkBA variant leads to EDA-ID
  • Dectin-1 mediated noncanonical NF-kB signaling
  • CLEC7A (Dectin-1) signaling
  • CD209 (DC-SIGN) signaling
  • CLEC7A/inflammasome pathway
  • The NLRP3 inflammasome
  • Transcriptional Regulation by VENTX
  • Interleukin-1 signaling
  • TRAF6 mediated NF-kB activation
  • Purinergic signaling in leishmaniasis infection
  • SARS-CoV-1 activates/modulates innate immune responses
  • Regulation of NFE2L2 gene expression
  • Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
  • Regulation of PD-L1(CD274) transcription
  • Glucosamine
  • Dimethyl fumarate
  • SC-236
Novel REPS2 RALBP1 associated Eps domain containing 2
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
Novel RNASEL ribonuclease L
  • OAS antiviral response
  • Interferon alpha/beta signaling
Novel RNF14 ring finger protein 14
  • Antigen processing: Ubiquitination & Proteasome degradation
Novel RNF4 ring finger protein 4
  • Processing of DNA double-strand break ends
  • Antigen processing: Ubiquitination & Proteasome degradation
Novel RNF6 ring finger protein 6
  • Antigen processing: Ubiquitination & Proteasome degradation
Novel RUNX1 RUNX family transcription factor 1
  • Pre-NOTCH Transcription and Translation
  • SLC-mediated transport of organic cations
  • RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
  • RUNX1 regulates estrogen receptor mediated transcription
  • Regulation of RUNX1 Expression and Activity
  • Regulation of RUNX1 Expression and Activity
  • RUNX1 regulates expression of components of tight junctions
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
  • RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • RUNX1 regulates transcription of genes involved in BCR signaling
  • RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
  • RUNX1 regulates transcription of genes involved in interleukin signaling
  • RUNX1 regulates transcription of genes involved in WNT signaling
  • RUNX2 regulates genes involved in differentiation of myeloid cells
  • RUNX3 regulates p14-ARF
  • Estrogen-dependent gene expression
  • Transcriptional regulation of granulopoiesis
  • SARS-CoV-1 activates/modulates innate immune responses
  • Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)
  • Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
  • Acute myeloid leukemia (AML)
  • Chronic myeloid leukemia (CML)
  • Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
Novel RUNX2 RUNX family transcription factor 2
  • Cleidocranial dysplasia
Novel SART3 spliceosome associated factor 3, U4/U6 recycling protein
  • Disseminated superficial actinic porokeratosis (DSAP)
Novel SENP2 SUMO specific peptidase 2
  • SUMO is proteolytically processed
Novel SFPQ splicing factor proline and glutamine rich
  • PTK6 Regulates Proteins Involved in RNA Processing
  • Suppression of apoptosis
  • Copper
  • Artenimol
Novel SH2D1A SH2 domain containing 1A
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
Novel SH2D1B SH2 domain containing 1B
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Novel SH2D2A SH2 domain containing 2A
  • VEGFA-VEGFR2 Pathway
Novel SH2D3C SH2 domain containing 3C
Novel SH3YL1 SH3 and SYLF domain containing 1
Novel SHB SH2 domain containing adaptor protein B
  • VEGFA-VEGFR2 Pathway
  • VEGFA-VEGFR2 Pathway

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