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cystathionine beta-synthase like |
- Cysteine formation from homocysteine
- Metabolism of ingested SeMet, Sec, MeSec into H2Se
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- Pyridoxal phosphate
- Ademetionine
- Serine
- Cysteine
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AAMP |
angio associated migratory cell protein |
- NOD1/2 Signaling Pathway
- Signaling by EGFR
- Signaling by VEGF
- Thromboxane signalling through TP receptor
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AARSD1 |
alanyl-tRNA synthetase domain containing 1 |
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AASS |
aminoadipate-semialdehyde synthase |
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- Glutamic acid
- NADH
- NADPH
- L-Saccharopine
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ABI1 |
abl interactor 1 |
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- VEGFA-VEGFR2 Pathway
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- RAC1 GTPase cycle
- RAC2 GTPase cycle
- RAC3 GTPase cycle
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
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ABI2 |
abl interactor 2 |
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- VEGFA-VEGFR2 Pathway
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- RAC1 GTPase cycle
- RAC2 GTPase cycle
- RAC3 GTPase cycle
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
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ABRAXAS1 |
abraxas 1, BRCA1 A complex subunit |
- Metalloprotease DUBs
- Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
- Nonhomologous End-Joining (NHEJ)
- Processing of DNA double-strand break ends
- G2/M DNA damage checkpoint
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ABRAXAS2 |
abraxas 2, BRISC complex subunit |
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ACOX1 |
acyl-CoA oxidase 1 |
- Peroxisomal protein import
- Peroxisomal protein import
- TYSND1 cleaves peroxisomal proteins
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- Flavin adenine dinucleotide
- (3R)-3-HYDROXYDODECANOIC ACID
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- Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
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ACTB |
actin beta |
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Gap junction degradation
- Formation of annular gap junctions
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- HATs acetylate histones
- Prefoldin mediated transfer of substrate to CCT/TriC
- Folding of actin by CCT/TriC
- EPHB-mediated forward signaling
- EPH-ephrin mediated repulsion of cells
- Adherens junctions interactions
- Adherens junctions interactions
- Recycling pathway of L1
- Recycling pathway of L1
- VEGFA-VEGFR2 Pathway
- Interaction between L1 and Ankyrins
- Interaction between L1 and Ankyrins
- Cell-extracellular matrix interactions
- B-WICH complex positively regulates rRNA expression
- RHO GTPases activate IQGAPs
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate Formins
- RHO GTPases Activate Formins
- MAP2K and MAPK activation
- UCH proteinases
- DNA Damage Recognition in GG-NER
- Signaling by moderate kinase activity BRAF mutants
- Signaling by high-kinase activity BRAF mutants
- Signaling by BRAF and RAF1 fusions
- Paradoxical activation of RAF signaling by kinase inactive BRAF
- Clathrin-mediated endocytosis
- RHOF GTPase cycle
- Signaling downstream of RAS mutants
- Signaling by RAF1 mutants
- Sensory processing of sound by inner hair cells of the cochlea
- Sensory processing of sound by outer hair cells of the cochlea
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
- Regulation of CDH1 Function
- Regulation of MITF-M-dependent genes involved in pigmentation
- Regulation of MITF-M-dependent genes involved in pigmentation
- Factors involved in megakaryocyte development and platelet production
- Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
- Formation of the dystrophin-glycoprotein complex (DGC)
- Formation of the dystrophin-glycoprotein complex (DGC)
- Formation of the canonical BAF (cBAF) complex
- Formation of the polybromo-BAF (pBAF) complex
- Formation of the embryonic stem cell BAF (esBAF) complex
- Formation of the non-canonical BAF (ncBAF) complex
- Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
- Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
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- Quercetin
- Phenethyl Isothiocyanate
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- Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
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ACTC1 |
actin alpha cardiac muscle 1 |
- Striated Muscle Contraction
- RHOA GTPase cycle
- RHOB GTPase cycle
- Regulation of CDH1 Function
- Formation of the dystrophin-glycoprotein complex (DGC)
- Formation of the dystrophin-glycoprotein complex (DGC)
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- Dilated cardiomyopathy (DCM)
- Hypertrophic cardiomyopathy (HCM)
- Atrial septal defect
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ACTL6A |
actin like 6A |
- HATs acetylate histones
- RMTs methylate histone arginines
- UCH proteinases
- DNA Damage Recognition in GG-NER
- RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
- Regulation of MITF-M-dependent genes involved in pigmentation
- Regulation of MITF-M-dependent genes involved in pigmentation
- Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
- Formation of the canonical BAF (cBAF) complex
- Formation of the polybromo-BAF (pBAF) complex
- Formation of the embryonic stem cell BAF (esBAF) complex
- Formation of the non-canonical BAF (ncBAF) complex
- Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
- Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
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ACTR3 |
actin related protein 3 |
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- EPHB-mediated forward signaling
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- Clathrin-mediated endocytosis
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
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- N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide
- (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
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ADPGK |
ADP dependent glucokinase |
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ADSL |
adenylosuccinate lyase |
- Purine ribonucleoside monophosphate biosynthesis
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- Adenylosuccinate lyase deficiency
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AGFG1 |
ArfGAP with FG repeats 1 |
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
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AHSA1 |
activator of HSP90 ATPase activity 1 |
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ALDH1A2 |
aldehyde dehydrogenase 1 family member A2 |
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ALDH1B1 |
aldehyde dehydrogenase 1 family member B1 |
- Ethanol oxidation
- Mitochondrial protein degradation
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ALDH2 |
aldehyde dehydrogenase 2 family member |
- Metabolism of serotonin
- Smooth Muscle Contraction
- Ethanol oxidation
- Mitochondrial protein degradation
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- NADH
- Guanidine
- Disulfiram
- Daidzin
- Crotonaldehyde
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- Acute alcohol sensitivity
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