DHX57 and RSPO4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DHX57	RSPO4
Description		DExH-box helicase 57	R-spondin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Region Extracellular Space
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Hydrolase Activity ATP Hydrolysis Activity Metal Ion Binding RNA Polymerase Binding	Signaling Receptor Binding Protein Binding Heparin Binding
	Biological Process	Positive Regulation Of Translation	Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Nail Development Limb Development Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways			Regulation of FZD by ubiquitination
Drugs
Diseases			Anonychia congenita
GWAS		Obesity-related traits ( 23251661)	Blood protein levels ( 30072576) Lean body mass ( 28552196) Logical memory (immediate recall) in Alzheimer's disease dementia ( 29274321)
Interacting Genes		25 interacting genes: CARD10 CBX2 CEP44 EIF4ENIF1 KRT31 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP9-4 NAA10 PCGF5 PLAGL2 RBMY1A1 RSPO4 ZNF473 ZNF587 ZNF837	15 interacting genes: ANKRD11 DHX57 GNG13 GPSM3 GUCD1 HGS KLHL38 LGR4 MAPK9 MKRN3 PIH1D2 STK16 USP20 ZNF330 ZNF77
Entrez ID		90957	343637
HPRD ID		09919	18788
Ensembl ID		ENSG00000163214	ENSG00000101282
Uniprot IDs		Q6P158	Q2I0M5
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament
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