CFHR5 and KCNK7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CFHR5	KCNK7
Description		complement factor H related 5	potassium two pore domain channel subfamily K member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Protein-containing Complex	Plasma Membrane Membrane Monoatomic Ion Channel Complex
	Molecular Function	Complement Component C3b Binding Protein Binding Identical Protein Binding Protein Heterodimerization Activity	Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity Potassium Ion Leak Channel Activity
	Biological Process	Complement Activation Complement Activation, Alternative Pathway Negative Regulation Of Protein Binding Cytolysis By Host Of Symbiont Cells	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Regulation of Complement cascade	Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) Phase 4 - resting membrane potential
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23536807 23577725) Age-related macular degeneration (extreme sampling) ( 23577725) Age-related macular degeneration (MTAG) ( 32277175) Asthma ( 29273806) Lupus nephritis in systemic lupus erythematosus ( 24925725) Matrix metalloproteinase-8 levels ( 29212897) Nephropathy ( 21399633)	Acne (severe) ( 24927181) Rosacea symptom severity ( 29771307)
Interacting Genes		21 interacting genes: ARL13B C3 CFTR CISD2 CREB3 CREB3L1 EBAG9 ERGIC3 FFAR2 GPX8 KCNK7 LMNA PANX1 SLC10A1 SLC18A2 SLC4A1 SLC71A2 STOM TMEM14B TMEM237 TMPRSS2	1 interacting genes: CFHR5
Entrez ID		81494	10089
HPRD ID		06508	06804
Ensembl ID		ENSG00000134389	ENSG00000173338
Uniprot IDs		Q9BXR6	Q3SYI1 Q9Y2U2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Bicarbonate Transmembrane Transporter Activity	Complement Activation, Alternative Pathway Cytolysis By Host Of Symbiont Cells Complement Component C3b Binding Biological Process Involved In Interaction With Symbiont Negative Regulation Of Protein Binding Regulation Of Protein Binding Complement Activation Killing By Host Of Symbiont Cells Killing Of Cells Of Another Organism Cell Killing Humoral Immune Response
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?