CELF4 and PCBP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CELF4	PCBP3
Description		CUGBP Elav-like family member 4	poly(rC) binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Postsynapse Ribonucleoprotein Complex	Nucleus Cytoplasm Cytosol Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	MRNA Regulatory Element Binding Translation Repressor Activity Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding BRE Binding	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding Protein Binding C-rich Single-stranded DNA Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Recognition MRNA Processing Germ Cell Development RNA Splicing Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Translation Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Excitatory Postsynaptic Potential Negative Regulation Of Excitatory Postsynaptic Potential Regulation Of Retina Development In Camera-type Eye	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II MRNA Metabolic Process Viral RNA Genome Replication
Pathways
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Daytime nap ( 33568662) Depression ( 33859377) Educational attainment ( 25201988) Experiencing mood swings ( 29500382) Feeling fed-up ( 29500382) Feeling guilty ( 29500382) Feeling hurt ( 29500382) Feeling miserable ( 29500382) Gastroesophageal reflux disease ( 34187846) General factor of neuroticism ( 30867560) HDL cholesterol levels in HIV infection ( 33109212) Household income ( 31844048) Household income (MTAG) ( 31844048) Mood instability ( 31168069) Neurociticism ( 29500382) Neuroticism ( 27089181 27067015) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Worry too long after an embarrassing experience ( 29500382)	A body shape index ( 34021172) Ankle injury ( 28957384) Daytime nap ( 33568662) Diffusing capacity of carbon monoxide ( 30694715) Insulin resistance/response ( 21901158) Intraocular pressure ( 29617998) Keratoconus ( 33649486) Low myopia ( 33830181) Macular thickness ( 30535121) Myopia ( 27182965) Refractive error ( 32231278) Spatial processing ( 31596458) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		10 interacting genes: APP LYST PCBP3 PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS2 TIAL1	17 interacting genes: APOBEC3C CELF4 DDIT4L HNRNPLL KRT81 MATR3 PTBP1 PTBP2 PUF60 QKI RBM47 RNF4 RUVBL1 SNRPA SREK1 SRSF3 ZC3HAV1
Entrez ID		56853	54039
HPRD ID		12534	10534
Ensembl ID		ENSG00000101489	ENSG00000183570
Uniprot IDs		Q9BZC1	P57721
PDB IDs		2DGP 2DNK
Enriched GO Terms of Interacting Partners?		Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle	Nucleic Acid Binding MRNA Processing Regulation Of RNA Splicing RNA Splicing RNA Binding MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome RNA Processing Regulation Of MRNA Processing MRNA Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Metabolic Process Regulation Of MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Pre-mRNA Binding Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Metabolic Process MRNA Splice Site Recognition Macromolecule Metabolic Process Nucleus Ribonucleoprotein Complex Regulation Of Gene Expression MRNA Splicing, Via Spliceosome Protein-RNA Complex Assembly Regulation Of Macromolecule Biosynthetic Process RNA Splicing, Via Transesterification Reactions Cytidine To Uridine Editing Base Conversion Or Substitution Editing Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Macromolecule Biosynthetic Process Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process RNA Localization Regulation Of RNA Metabolic Process Regulation Of Metabolic Process MiRNA Binding Spliceosomal Complex Positive Regulation Of Gene Expression Positive Regulation Of RNA Splicing Regulation Of Nucleobase-containing Compound Metabolic Process Internal N(7)-methylguanine-containing RNA Reader Activity Regulation Of Retina Development In Camera-type Eye Negative Regulation Of Viral Genome Replication Positive Regulation Of Macromolecule Metabolic Process Poly-pyrimidine Tract Binding Protein-RNA Sequence-specific Adaptor Activity
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