RHCG and ERMP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RHCG	ERMP1
Description		Rh family C glycoprotein	endoplasmic reticulum metallopeptidase 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Ammonium Channel Activity Ankyrin Binding Carbon Dioxide Transmembrane Transporter Activity Identical Protein Binding	Protein Binding Peptidase Activity Metalloexopeptidase Activity Metallopeptidase Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Intracellular Monoatomic Ion Homeostasis Regulation Of PH Amine Transport Epithelial Cell Differentiation Carbon Dioxide Transmembrane Transport Homeostatic Process Transepithelial Ammonium Transport Ammonium Transmembrane Transport Ammonium Homeostasis	Proteolysis Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress
Pathways		Rhesus glycoproteins mediate ammonium transport
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Dentures ( 31235808) Femur bone mineral density x serum urate levels interaction ( 34046847) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)	Asthma ( 31619474 31959851) Blond vs. brown/black hair color ( 30531825) Waist-hip ratio ( 28552196)
Interacting Genes		13 interacting genes: ARLN C1QL4 CXCL9 ERMP1 FXYD6 GPR25 IGFBP5 MS4A13 TMEM60 TMEM97 TRARG1 UPK1B YIPF6	39 interacting genes: AQP2 AQP6 ATP1B4 BCL2L13 BSCL2 CD200R1 CLDN5 CLDN7 CLDN9 CLEC2D CREB3L1 ERVFRD-1 FAM209A FKBP7 FNDC9 GJA8 GPR42 GPRC5D HHLA2 HIBADH IER3IP1 IFNGR2 KCNN3 KLRC1 LYPD5 MR1 PDCD1LG2 PEX12 RHCG SLC13A4 SLC18A1 SLC22A23 SLC23A2 SLC7A14 SPAG4 SSMEM1 TMEM237 TMEM45A TMEM80
Entrez ID		51458	79956
HPRD ID		16102	17227
Ensembl ID		ENSG00000140519	ENSG00000099219
Uniprot IDs		Q9UBD6	A0A8I5KNY4 A0A8I5KXJ0 E7ER77 Q6ZMD3 Q7Z2K6
PDB IDs		3HD6
Enriched GO Terms of Interacting Partners?			Membrane Transmembrane Transport Plasma Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Transmembrane Transporter Activity Protein Binding Renal Water Transport Bicellular Tight Junction Assembly External Side Of Plasma Membrane Ammonium Channel Activity Ammonium Transmembrane Transport Tight Junction Assembly Nuclear Inner Membrane Tight Junction Organization Amine Transport Water Channel Activity Carbon Dioxide Transport Structural Molecule Activity
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