KRTAP12-1 and TOX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP12-1	TOX
Description		keratin associated protein 12-1	thymocyte selection associated high mobility group box
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Nucleus
	Molecular Function	Protein Binding	DNA Binding Protein Binding Chromatin DNA Binding
	Biological Process		Natural Killer Cell Differentiation CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Lineage Commitment NK T Cell Lineage Commitment Leukocyte Differentiation Chromatin Organization Regulation Of Transcription By RNA Polymerase II Nervous System Development Positive Regulation Of Neuron Projection Development Cerebral Cortex Neuron Differentiation Lymphocyte Differentiation Positive Regulation Of Natural Killer Cell Differentiation CD4-positive, Alpha-beta T Cell Lineage Commitment CD8-positive, Alpha-beta T Cell Lineage Commitment Positive Regulation Of Transcription By RNA Polymerase II Lymph Node Development Peyer's Patch Development Regulation Of Positive Thymic T Cell Selection Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Keratinization
Drugs
Diseases
GWAS			Chronotype ( 30696823) Cognitive performance ( 19734545) Height ( 31562340) High myopia ( 31816047) Hyperopia ( 25233373) Mercury levels ( 26025379) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Myopia ( 27182965 25233373) Oily fish consumption ( 32066663) Parental longevity (father's attained age) ( 29227965) Pork consumption ( 32066663) Psychological resilience (outcome-based) ( 31081985) Refractive astigmatism ( 25367360) Refractive error ( 32231278 23396134) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 33082346 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Superior temporal sulcus banks volume ( 31530798) Systolic blood pressure ( 30224653) Type 1 diabetes ( 34012112) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		62 interacting genes: CATSPER1 CHRD CYSRT1 DHRS1 ENKD1 FHL3 GATA3 GPRIN2 GRN HOXA1 HOXC8 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP3-2 KRTAP4-4 KRTAP4-5 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE3A LCE5A MEOX2 MGAT5B NBPF19 NEU4 NOTCH2NLA OTX1 PDIA2 PDIA4 PEF1 POU2AF1 POU4F2 PRR35 RBPMS SMCP TOX TRIP13 UBQLN2 VGLL3 ZIC1	6 interacting genes: BANP DMRTB1 GRAP KRTAP12-1 KRTAP26-1 ZDHHC17
Entrez ID		353332	9760
HPRD ID		11197	12113
Ensembl ID		ENSG00000187175	ENSG00000198846
Uniprot IDs		P59990	O94900
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Identical Protein Binding Protein Binding	Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Keratin Filament Intermediate Filament Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity
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