TRPM5 and HPCAL4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRPM5	HPCAL4
Description		transient receptor potential cation channel subfamily M member 5	hippocalcin like 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite Monoatomic Ion Channel Complex Neuronal Cell Body
	Molecular Function	Monoatomic Ion Channel Activity Calcium-activated Cation Channel Activity Potassium Channel Activity Sodium Channel Activity Calcium Ion Binding Protein Binding Identical Protein Binding Metal Ion Binding Metal Ion Transmembrane Transporter Activity	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Monoatomic Ion Transport Metal Ion Transport Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Transmembrane Transport Calcium Ion Transmembrane Transport Potassium Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport	Central Nervous System Development Response To Heat Regulation Of Signal Transduction
Pathways		TRP channels Sensory perception of sweet, bitter, and umami (glutamate) taste
Drugs
Diseases
GWAS		Malaria ( 31844061) Metabolite levels ( 23823483)	Bone mineral density (Ward's triangle area) ( 27397699)
Interacting Genes		1 interacting genes: HPCAL4	16 interacting genes: ANKRD33 AQP4 CDSN CEACAM6 DTX2 F3 FAM131C LITAF MSRA SCMH1 SPRED1 TEX13B TRPM5 TSC22D3 TTC12 UBE3A
Entrez ID		29850	51440
HPRD ID		16064	17113
Ensembl ID		ENSG00000070985	ENSG00000116983
Uniprot IDs		Q9NZQ8	B4DGW9 Q9UM19
PDB IDs
Enriched GO Terms of Interacting Partners?		Central Nervous System Development Response To Temperature Stimulus Calcium Channel Regulator Activity Response To Heat
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