MMADHC and MMACHC

Number of citations of the paper that reports this interaction (PubMedID 21071249)
0

Data Source:
BioGRID (pull down, two hybrid)

		MMADHC	MMACHC
Description		metabolism of cobalamin associated D	metabolism of cobalamin associated C
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Cytoplasm Cytosol
	Molecular Function	Protein Binding Molecular Carrier Activity	Protein Binding Oxidoreductase Activity Transferase Activity Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups Cobalamin Binding Demethylase Activity Cyanocobalamin Reductase (cyanide-eliminating) (NADP+) Activity Protein Homodimerization Activity Glutathione Binding FAD Binding
	Biological Process	Cobalamin Metabolic Process	Glutathione Metabolic Process Cobalamin Metabolic Process Demethylation
Pathways		Defective MMADHC causes MMAHCD Cobalamin (Cbl) metabolism	Defective MMADHC causes MMAHCD Defective MMACHC causes MAHCC Cobalamin (Cbl) metabolism
Drugs			Cyanocobalamin Hydroxocobalamin
Diseases		Methylmalonic aciduria (MMA)	Methylmalonic aciduria (MMA)
GWAS		Daytime sleep phenotypes ( 27126917) Liver enzyme levels (alanine transaminase) ( 24124411) Neonatal total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095)	Homocysteine levels ( 23824729)
Interacting Genes		6 interacting genes: CINP CREB5 MMACHC POU4F2 PRNP TBC1D7	1 interacting genes: MMADHC
Entrez ID		27249	25974
HPRD ID		10781	18585
Ensembl ID		ENSG00000168288	ENSG00000132763
Uniprot IDs		Q9H3L0	A0A0C4DGU2 Q9Y4U1
PDB IDs		5CUZ 5CV0 6X8Z	3SBY 3SBZ 3SC0 3SOM 5UOS 7WUZ
Enriched GO Terms of Interacting Partners?			Histone H3K36me2/H3K36me3 Demethylase Activity Cardiac Muscle Hypertrophy In Response To Stress Histone H3K9 Demethylase Activity Histone H4K20me2 Reader Activity Histone H3K36 Demethylase Activity Histone H3K9me2/H3K9me3 Demethylase Activity Molecular Carrier Activity Cobalamin Metabolic Process Cardiac Muscle Hypertrophy Histone Demethylase Activity Muscle Hypertrophy Pericentric Heterochromatin Tetrapyrrole Metabolic Process Dioxygenase Activity Negative Regulation Of Autophagy
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?