NKAPL and DDX41

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NKAPL	DDX41
Description		NFKB activating protein like	DEAD-box helicase 41
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Endoplasmic Reticulum Cytosol Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Chromatin Binding Protein Binding	Nucleotide Binding Nucleic Acid Binding DNA Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Hydrolase Activity ATP Hydrolysis Activity Metal Ion Binding
	Biological Process	Spermatogenesis Regulation Of Gene Expression Cell Differentiation	MRNA Splicing, Via Spliceosome MRNA Processing Apoptotic Process Cell Population Proliferation RNA Splicing Cell Differentiation Positive Regulation Of Type I Interferon Production Cellular Response To Interferon-beta Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus CGAS/STING Signaling Pathway
Pathways			STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA IRF3-mediated induction of type I IFN mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Refractive error ( 32231278) Schizophrenia ( 22037552) Subcortical volume (MOSTest) ( 32665545)	Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: ARL6IP4 BRCA1 CLK3 DDX41 NKAPD1 SREK1IP1 ZNF417 ZNF587	11 interacting genes: AIDA CEBPA CEP70 CHAF1A KLC2 NKAPL OGT SIAH1 TRIM26 TRIM41 TUBG1
Entrez ID		222698	51428
HPRD ID		16664	10490
Ensembl ID		ENSG00000189134	ENSG00000183258
Uniprot IDs		Q5M9Q1	B3KRK2 Q9UJV9
PDB IDs			2P6N 5GVR 5GVS 5H1Y 8C6J
Enriched GO Terms of Interacting Partners?
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