HCST and STARD3NL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HCST	STARD3NL
Description		hematopoietic cell signal transducer	STARD3 N-terminal like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane	Lysosomal Membrane Endosome Endoplasmic Reticulum Membrane Cytosol Membrane Late Endosome Membrane Organelle Membrane Contact Site Endoplasmic Reticulum-endosome Membrane Contact Site
	Molecular Function	Signaling Receptor Binding Protein Binding Protein-macromolecule Adaptor Activity Phosphatidylinositol 3-kinase Binding	Protein Binding Cholesterol Binding Protein Homodimerization Activity
	Biological Process	Protein Phosphorylation Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction	Cholesterol Transport Vesicle Tethering To Endoplasmic Reticulum
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Pregnenolone biosynthesis
Drugs
Diseases
GWAS			Bone mineral density (spine) ( 19801982) Fractures ( 30598549 30158200) Frontotemporal dementia with GRN mutation ( 29724592) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 28869591 30598549 31453325) Heel bone mineral density variance ( 31453325) Height ( 25429064 25282103 31562340 20881960) Lumbar spine bone mineral density ( 22504420) Lumbar spine bone mineral density (integral) ( 27476799) Mosquito bite size ( 28199695) Rosacea symptom severity ( 29771307) Treatment response for severe sepsis ( 22310353)
Interacting Genes		6 interacting genes: KLRK1 PIK3R1 SEC22A SPOP STARD3NL VSTM1	3 interacting genes: CHRM5 ELK1 HCST
Entrez ID		10870	83930
HPRD ID		04971	18117
Ensembl ID		ENSG00000126264	ENSG00000010270
Uniprot IDs		Q9UBK5	C9JKL2 O95772
PDB IDs
Enriched GO Terms of Interacting Partners?		Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity	G Protein-coupled Acetylcholine Receptor Activity Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Gastric Acid Secretion Regulation Of Phosphatidylinositol Dephosphorylation Cellular Response To Testosterone Stimulus Mediator Complex Binding Hippocampal Neuron Apoptotic Process Dendrite Transcription Regulator Activator Activity Regulation Of Dephosphorylation Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity G Protein-coupled Acetylcholine Receptor Signaling Pathway Transmission Of Nerve Impulse Dopamine Transport Phosphatidylinositol 3-kinase Binding
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