EMG1 and FAM74A4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

		EMG1	FAM74A4
Description		EMG1 N1-specific pseudouridine methyltransferase	family with sequence similarity 74 member A4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Small-subunit Processome
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity Transferase Activity RRNA Binding Identical Protein Binding RRNA (pseudouridine) Methyltransferase Activity
	Biological Process	Blastocyst Development RRNA Processing Nucleologenesis Methylation Ribosome Biogenesis Ribosomal Small Subunit Biogenesis RRNA Base Methylation
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Bowen-Conradi syndrome (BCS)
GWAS
Interacting Genes		20 interacting genes: ANXA3 APP CEBPA CFTR CTSE FAM74A4 FAM98A HIVEP1 HSD3B7 IL7R KHDRBS1 MCPH1 NAA80 PRC1 PSMB7 PSME1 SLC25A38 SUMO2 ZCCHC9 ZNF768	26 interacting genes: CCDC85B CCNDBP1 CEP44 EFEMP2 EMG1 HMBOX1 IKZF1 KRT31 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 LZTS2 MEOX2 MTUS2 NOTCH2NLA PDE4DIP PHC2 RPGRIP1 STX11 TCF4 TMCC2
Entrez ID		10436	401508
HPRD ID		12803	16982
Ensembl ID		ENSG00000126749	ENSG00000293075
Uniprot IDs		Q92979
PDB IDs		5FAI 7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?			Intermediate Filament Keratin Filament Identical Protein Binding Centrosome
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