PSPH

Description		phosphoserine phosphatase
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Magnesium Ion Binding Hydrolase Activity L-phosphoserine Phosphatase Activity Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	In Utero Embryonic Development L-serine Metabolic Process L-serine Biosynthetic Process Amino Acid Biosynthetic Process Response To Mechanical Stimulus Response To Nutrient Levels Response To Testosterone
Pathways		Serine metabolism
Drugs		Zinc 3-Phosphono-D-alanine Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Alanine aminotransferase levels ( 33339817 33547301) Estimated glomerular filtration rate ( 31015462) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glycine levels ( 30837465 31070104) Macular telangiectasia type 2 ( 28250457 33654266) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma homocysteine levels (post-methionine load test) ( 24651765) Serum metabolite levels ( 33031748)
Novel Interacting Genes		1 novel interacting genes: ITGB8
Interacting Genes		2 interacting genes: ATXN1 UBC
Entrez ID		5723
HPRD ID		01406
Ensembl ID		ENSG00000146733
Uniprot IDs		P78330
PDB IDs		1L8L 1L8O 1NNL 6HYJ 6HYY 6Q6J
Enriched GO Terms of Interacting Partners?
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