MOGS

Description		mannosyl-oligosaccharide glucosidase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Extracellular Exosome
	Molecular Function	Glc3Man9GlcNAc2 Oligosaccharide Glucosidase Activity Glucosidase Activity Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds
	Biological Process	Carbohydrate Metabolic Process Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process Viral Protein Processing
Pathways		Defective MOGS causes CDG-2b N-glycan trimming in the ER and Calnexin/Calreticulin cycle Maturation of spike protein Maturation of spike protein Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type II
GWAS
Novel Interacting Genes		8 novel interacting genes: C1D ETAA1 EXOC6B MXD1 PCBP1 RAB11FIP5 REL VPS54
Interacting Genes		1 interacting genes: CHGB
Entrez ID		7841
HPRD ID		03214
Ensembl ID		ENSG00000115275
Uniprot IDs		A0A384MDR6 Q13724 Q58F09
PDB IDs
Enriched GO Terms of Interacting Partners?
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