ADRBK1 |
adrenergic, beta, receptor kinase 1 |
- G alpha (q) signalling events
- Ca-dependent events
- Signaling by GPCR
- CaM pathway
- Phospholipase C-mediated cascade
- Signaling by FGFR in disease
- Signaling by EGFRvIII in Cancer
- PLCG1 events in ERBB2 signaling
- DAG and IP3 signaling
- CaM pathway
- DAP12 signaling
- Gastrin-CREB signalling pathway via PKC and MAPK
- Hedgehog 'on' state
- Downstream signaling of activated FGFR
- Innate Immune System
- Signaling by PDGF
- Calmodulin induced events
- Signalling by NGF
- DAP12 interactions
- PLC beta mediated events
- Opioid Signalling
- Signaling by Ligand-Responsive EGFR Variants in Cancer
- NGF signalling via TRKA from the plasma membrane
- G-protein mediated events
- Signaling by Overexpressed Wild-Type EGFR in Cancer
- Signaling by FGFR
- EGFR interacts with phospholipase C-gamma
- Signaling by ERBB2
- G alpha (q) signalling events
- Signaling by EGFR
- GPCR downstream signaling
- Calmodulin induced events
- Downstream signal transduction
- PLC-gamma1 signalling
- Signaling by Hedgehog
- Signaling by EGFR in Cancer
- Activation of SMO
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ARR3 |
arrestin 3, retinal (X-arrestin) |
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DERL1 |
derlin 1 |
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GNGT1 |
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 |
- Signaling by GPCR
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- ADP signalling through P2Y purinoceptor 1
- Integration of energy metabolism
- Activation of GABAB receptors
- G alpha (s) signalling events
- Glucagon-type ligand receptors
- G beta:gamma signalling through PLC beta
- Signaling by Wnt
- Metabolic disorders of biological oxidation enzymes
- G protein gated Potassium channels
- Olfactory Signaling Pathway
- Gastrin-CREB signalling pathway via PKC and MAPK
- Thromboxane signalling through TP receptor
- G alpha (z) signalling events
- G alpha (i) signalling events
- Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
- ADP signalling through P2Y purinoceptor 12
- Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
- Inwardly rectifying K+ channels
- G-protein beta:gamma signalling
- Opioid Signalling
- Activation of Kainate Receptors upon glutamate binding
- Diseases associated with visual transduction
- Aquaporin-mediated transport
- Adrenaline,noradrenaline inhibits insulin secretion
- G alpha (q) signalling events
- GPCR downstream signaling
- Platelet homeostasis
- Platelet activation, signaling and aggregation
- Transmission across Chemical Synapses
- G alpha (q) signalling events
- Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
- Signal amplification
- Potassium Channels
- Activation of the phototransduction cascade
- Inactivation, recovery and regulation of the phototransduction cascade
- G beta:gamma signalling through PI3Kgamma
- The phototransduction cascade
- G alpha (12/13) signalling events
- Class B/2 (Secretin family receptors)
- Prostacyclin signalling through prostacyclin receptor
- GABA B receptor activation
- GABA receptor activation
- Activation of G protein gated Potassium channels
- Vasopressin regulates renal water homeostasis via Aquaporins
- Regulation of insulin secretion
- GPCR ligand binding
- beta-catenin independent WNT signaling
- Thrombin signalling through proteinase activated receptors (PARs)
- Presynaptic function of Kainate receptors
- Visual phototransduction
- Ca2+ pathway
- G-protein activation
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GRK1 |
G protein-coupled receptor kinase 1 |
- Inactivation, recovery and regulation of the phototransduction cascade
- Visual phototransduction
- The phototransduction cascade
- Diseases associated with visual transduction
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GRK5 |
G protein-coupled receptor kinase 5 |
- G alpha (q) signalling events
- G alpha (q) signalling events
- Signaling by GPCR
- GPCR downstream signaling
- Gastrin-CREB signalling pathway via PKC and MAPK
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GRK6 |
G protein-coupled receptor kinase 6 |
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PPP2CA |
protein phosphatase 2, catalytic subunit, alpha isozyme |
- Signaling by GPCR
- Integration of energy metabolism
- Signaling by FGFR in disease
- Mitotic Prophase
- misspliced GSK3beta mutants stabilize beta-catenin
- T41 mutants of beta-catenin aren't phosphorylated
- ERKs are inactivated
- truncated APC mutants destabilize the destruction complex
- TCF7L2 mutants don't bind CTBP
- Glycolysis
- Signaling by Wnt
- Glucose metabolism
- Toll Like Receptor TLR1:TLR2 Cascade
- Degradation of beta-catenin by the destruction complex
- Toll Like Receptor 5 (TLR5) Cascade
- RNF mutants show enhanced WNT signaling and proliferation
- Myoclonic epilepsy of Lafora
- S33 mutants of beta-catenin aren't phosphorylated
- AXIN mutants destabilize the destruction complex, activating WNT signaling
- G1/S Transition
- Glycogen storage diseases
- MyD88 dependent cascade initiated on endosome
- Toll Like Receptor 9 (TLR9) Cascade
- Beta-catenin phosphorylation cascade
- Initiation of Nuclear Envelope Reformation
- Mitotic G1-G1/S phases
- ERK/MAPK targets
- Negative regulation of FGFR signaling
- truncations of AMER1 destabilize the destruction complex
- misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
- TRIF-mediated TLR3/TLR4 signaling
- Opioid Signalling
- phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex
- AXIN missense mutants destabilize the destruction complex
- S45 mutants of beta-catenin aren't phosphorylated
- Spry regulation of FGF signaling
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
- Toll Like Receptor 2 (TLR2) Cascade
- Platelet homeostasis
- deletions in the AMER1 gene destabilize the destruction complex
- Platelet sensitization by LDL
- AMER1 mutants destabilize the destruction complex
- Resolution of Sister Chromatid Cohesion
- Toll Like Receptor 3 (TLR3) Cascade
- Toll Like Receptor 4 (TLR4) Cascade
- Metabolism of carbohydrates
- Mitotic G2-G2/M phases
- Mitotic Metaphase and Anaphase
- Adaptive Immune System
- PP2A-mediated dephosphorylation of key metabolic factors
- MASTL Facilitates Mitotic Progression
- Mitotic Prometaphase
- Costimulation by the CD28 family
- Separation of Sister Chromatids
- APC truncation mutants have impaired AXIN binding
- Toll Like Receptor 7/8 (TLR7/8) Cascade
- G2/M Transition
- Mitotic Anaphase
- M Phase
- Toll Like Receptor TLR6:TLR2 Cascade
- APC truncation mutants are not K63 polyubiquitinated
- disassembly of the destruction complex and recruitment of AXIN to the membrane
- Activated TLR4 signalling
- S37 mutants of beta-catenin aren't phosphorylated
- MyD88 cascade initiated on plasma membrane
- Cyclin A/B1 associated events during G2/M transition
- XAV939 inhibits tankyrase, stabilizing AXIN
- DARPP-32 events
- MyD88:Mal cascade initiated on plasma membrane
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
- Nuclear Envelope Reassembly
- Innate Immune System
- Nonsense-Mediated Decay (NMD)
- E2F mediated regulation of DNA replication
- ERKs are inactivated
- Signalling by NGF
- MAP kinase activation in TLR cascade
- CTLA4 inhibitory signaling
- G1 Phase
- NGF signalling via TRKA from the plasma membrane
- MyD88-independent cascade
- Cell Cycle, Mitotic
- Signaling by FGFR
- Toll-Like Receptors Cascades
- Cyclin D associated events in G1
- Toll Like Receptor 10 (TLR10) Cascade
- TCF dependent signaling in response to WNT
- ERK/MAPK targets
- deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling
- MAPK targets/ Nuclear events mediated by MAP kinases
- Signaling by WNT in cancer
- Inhibition of replication initiation of damaged DNA by RB1/E2F1
- Nuclear Events (kinase and transcription factor activation)
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PRKCA |
protein kinase C, alpha |
- Ca-dependent events
- Signaling by GPCR
- CaM pathway
- Signaling by FGFR in disease
- Phospholipase C-mediated cascade
- Integration of energy metabolism
- Mitotic Prophase
- Signaling by Wnt
- Signaling by EGFRvIII in Cancer
- PLCG1 events in ERBB2 signaling
- Signaling by SCF-KIT
- DAP12 signaling
- Regulation of KIT signaling
- Gastrin-CREB signalling pathway via PKC and MAPK
- Response to elevated platelet cytosolic Ca2+
- G alpha (z) signalling events
- Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
- Signaling by PDGF
- Calmodulin induced events
- DAP12 interactions
- Regulation of mRNA stability by proteins that bind AU-rich elements
- Opioid Signalling
- Diseases associated with visual transduction
- EGFR interacts with phospholipase C-gamma
- Signaling by ERBB2
- Signaling by EGFR
- Syndecan interactions
- GPCR downstream signaling
- Signaling by VEGF
- Calmodulin induced events
- Downstream signal transduction
- WNT5A-dependent internalization of FZD4
- Signaling by EGFR in Cancer
- Platelet activation, signaling and aggregation
- PCP/CE pathway
- Transmission across Chemical Synapses
- Trafficking of GluR2-containing AMPA receptors
- Nuclear Envelope Breakdown
- HuR stabilizes mRNA
- DAG and IP3 signaling
- M Phase
- VEGFA-VEGFR2 Pathway
- CaM pathway
- Inactivation, recovery and regulation of the phototransduction cascade
- EGFR Transactivation by Gastrin
- VEGFR2 mediated cell proliferation
- Downstream signaling of activated FGFR
- The phototransduction cascade
- Disinhibition of SNARE formation
- Innate Immune System
- Signalling by NGF
- PLC beta mediated events
- Regulation of insulin secretion
- Depolymerisation of the Nuclear Lamina
- Signaling by Ligand-Responsive EGFR Variants in Cancer
- NGF signalling via TRKA from the plasma membrane
- G-protein mediated events
- Non-integrin membrane-ECM interactions
- Signaling by Overexpressed Wild-Type EGFR in Cancer
- Trafficking of AMPA receptors
- Cell Cycle, Mitotic
- Signaling by FGFR
- beta-catenin independent WNT signaling
- Acetylcholine regulates insulin secretion
- Visual phototransduction
- Ca2+ pathway
- PLC-gamma1 signalling
- Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
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- Phosphatidylserine
- Vitamin E
- Ingenol Mebutate
- Ellagic Acid
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SAG |
S-antigen; retina and pineal gland (arrestin) |
- Activation of the phototransduction cascade
- Inactivation, recovery and regulation of the phototransduction cascade
- Visual phototransduction
- The phototransduction cascade
- Diseases associated with visual transduction
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