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XAGE1E and PLA2G4A
Number of citations of the paper that reports this interaction (PMID
18330356
)
4
Data Source:
BioGRID
(two hybrid)
XAGE1E
PLA2G4A
Gene Name
X antigen family, member 1E
phospholipase A2, group IVA (cytosolic, calcium-dependent)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Mitochondrial Inner Membrane
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Cytoplasmic Membrane-bounded Vesicle
Molecular Function
Lysophospholipase Activity
Phospholipase A2 Activity
Calcium Ion Binding
Calcium-dependent Phospholipid Binding
Calcium-dependent Phospholipase A2 Activity
Biological Process
Phospholipid Metabolic Process
Phosphatidic Acid Biosynthetic Process
Platelet Activating Factor Biosynthetic Process
Icosanoid Metabolic Process
Blood Coagulation
Phospholipid Catabolic Process
Arachidonic Acid Metabolic Process
Platelet Activation
Cardiolipin Acyl-chain Remodeling
Phosphatidylglycerol Acyl-chain Remodeling
Phosphatidylinositol Acyl-chain Remodeling
Phosphatidylserine Acyl-chain Remodeling
Phosphatidylcholine Acyl-chain Remodeling
Phosphatidylethanolamine Acyl-chain Remodeling
Regulation Of Cell Proliferation
Small Molecule Metabolic Process
Icosanoid Biosynthetic Process
Glycerophospholipid Biosynthetic Process
Arachidonic Acid Secretion
Cellular Response To Antibiotic
Pathways
phospho-PLA2 pathway
Ca-dependent events
Signaling by GPCR
Acyl chain remodeling of CL
ADP signalling through P2Y purinoceptor 1
Hydrolysis of LPC
Acyl chain remodelling of PE
Metabolism of lipids and lipoproteins
Signal amplification
Arachidonic acid metabolism
Phospholipid metabolism
Acyl chain remodelling of PC
Synthesis of PA
PLC beta mediated events
Opioid Signalling
Glycerophospholipid biosynthesis
G-protein mediated events
Acyl chain remodelling of PS
Acyl chain remodelling of PG
Platelet homeostasis
Acyl chain remodelling of PI
Platelet sensitization by LDL
Platelet activation, signaling and aggregation
Drugs
Fluticasone Propionate
Quinacrine
Niflumic Acid
Diseases
GWAS
Epilepsy (generalized) (
22949513
)
Knee osteoarthritis (
18471798
)
Protein-Protein Interactions
1 interactors:
PLA2G4A
18 interactors:
C17orf59
CAP1
CASP1
CASP3
CASP4
EHD1
JAK1
KAT5
MAPK14
MAPKAPK5
MKNK1
PLA2G5
RELA
RPS6KA5
SHBG
UBXN1
VIM
XAGE1E
Entrez ID
653067
5321
HPRD ID
19219
08986
Ensembl ID
ENSG00000204375
ENSG00000116711
Uniprot IDs
Q9HD64
E7EU42
P47712
PDB IDs
1BCI
1CJY
1RLW
Enriched GO Terms of Interacting Partners
?
Platelet Activating Factor Biosynthetic Process
Platelet Activating Factor Metabolic Process
Cardiolipin Acyl-chain Remodeling
Cardiolipin Metabolic Process
Arachidonic Acid Secretion
Phosphatidylinositol Acyl-chain Remodeling
Phosphatidylglycerol Acyl-chain Remodeling
Phosphatidylserine Acyl-chain Remodeling
Cellular Response To Antibiotic
Phosphatidylethanolamine Acyl-chain Remodeling
Phosphatidylcholine Acyl-chain Remodeling
Cellular Response To Toxic Substance
Phosphatidic Acid Biosynthetic Process
Phosphatidic Acid Metabolic Process
Phospholipid Catabolic Process
Phosphatidylserine Metabolic Process
Long-chain Fatty Acid Transport
Icosanoid Biosynthetic Process
Phosphatidylcholine Metabolic Process
Response To Antibiotic
Acid Secretion
Fatty Acid Transport
Arachidonic Acid Metabolic Process
Icosanoid Metabolic Process
Unsaturated Fatty Acid Metabolic Process
Long-chain Fatty Acid Metabolic Process
Cellular Biogenic Amine Metabolic Process
Monocarboxylic Acid Transport
Amine Metabolic Process
Organophosphate Catabolic Process
Cellular Lipid Catabolic Process
Response To Toxic Substance
Platelet Activation
Glycerophospholipid Biosynthetic Process
Phosphatidylinositol Metabolic Process
Phospholipid Biosynthetic Process
Lipid Catabolic Process
Cellular Modified Amino Acid Metabolic Process
Lipid Transport
Glycerophospholipid Metabolic Process
Carboxylic Acid Transport
Organic Acid Transport
Fatty Acid Metabolic Process
Lipid Localization
Alcohol Metabolic Process
Glycerolipid Metabolic Process
Phospholipid Metabolic Process
Blood Coagulation
Hemostasis
Organic Anion Transport
Cellular Response To Organic Substance
Response To Organic Substance
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Execution Phase Of Apoptosis
Regulation Of Protein Metabolic Process
Toll-like Receptor 4 Signaling Pathway
Regulation Of Innate Immune Response
Toll-like Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Growth Factor Stimulus
Response To Stress
Apoptotic Process
Response To Growth Factor
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Programmed Cell Death
Activation Of Innate Immune Response
Cell Death
Death
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Response To Cytokine
Positive Regulation Of Innate Immune Response
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Innate Immune Response
Toll-like Receptor 9 Signaling Pathway
Intracellular Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Protein Metabolic Process
Regulation Of Cytokine Production
Stress-induced Premature Senescence
Positive Regulation Of Myoblast Fusion
Response To Muramyl Dipeptide
Response To Abiotic Stimulus
Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion
Regulation Of Myoblast Fusion
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Cellular Protein Metabolic Process
Peptidyl-serine Phosphorylation
Response To Tumor Necrosis Factor
Signal Transduction
Tagcloud
?
11beta
9alpha
abcc4
akr1b1
akr1c1
akr1c3
catalyze
diseased
endometriosis
endometriotic
endometrium
gynecological
hieec
hiesc
hpgd
hpgds
infertility
peritoneal
pgd2
pgf2alpha
pgh2
provokes
ptgds
ptgfr
ptgs2
reaches
slco2a
synthases
Tagcloud (Difference)
?
11beta
9alpha
abcc4
akr1b1
akr1c1
akr1c3
catalyze
diseased
endometriosis
endometriotic
endometrium
gynecological
hieec
hiesc
hpgd
hpgds
infertility
peritoneal
pgd2
pgf2alpha
pgh2
provokes
ptgds
ptgfr
ptgs2
reaches
slco2a
synthases
Tagcloud (Intersection)
?