FPR1

Gene Name		formyl peptide receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Plasma Membrane Integral Component Of Membrane
	Molecular Function	Receptor Activity N-formyl Peptide Receptor Activity Protein Binding RAGE Receptor Binding
	Biological Process	Activation Of MAPK Activity Movement Of Cell Or Subcellular Component Chemotaxis Signal Transduction G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Nitric Oxide Mediated Signal Transduction
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Formyl peptide receptors bind formyl peptides and many other ligands
Drugs		Nedocromil
Diseases
GWAS
Protein-protein Interactions		5 interactors: ACTG1 ADRBK1 ANXA1 GNAI2 SAA1
Entrez ID		2357
HPRD ID		00646
Ensembl ID
Uniprot IDs		P21462
PDB IDs
Enriched GO Terms of Interacting Partners?		G-protein Coupled Acetylcholine Receptor Signaling Pathway Cell Activation Platelet Activation Defense Response Blood Coagulation Hemostasis Response To Stress Regulation Of Phospholipase Activity Regulation Of Body Fluid Levels Wound Healing Regulation Of Secretion Endocytosis Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Neutrophil Clearance Response To Wounding Positive Regulation Of Transport Regulation Of Cytokine Secretion Immune System Process Innate Immune Response DNA Rewinding Positive Regulation Of Neutrophil Apoptotic Process Negative Regulation Of Phospholipase A2 Activity Regulation Of Cellular Localization Negative Regulation Of Interleukin-8 Secretion Prolactin Secretion Positive Regulation Of Prostaglandin Biosynthetic Process Negative Regulation Of Phospholipase Activity Cell Surface Receptor Signaling Pathway Immune Response Negative Regulation Of Striated Muscle Contraction Regulation Of The Force Of Heart Contraction By Chemical Signal Cellular Response To Stimulus Homeostatic Process Positive Regulation Of Secretion Homotypic Cell-cell Adhesion Tachykinin Receptor Signaling Pathway Vesicle-mediated Transport Positive Regulation Of Myeloid Cell Apoptotic Process Receptor-mediated Endocytosis Regulation Of Phospholipase A2 Activity Positive Regulation Of Catecholamine Secretion Movement Of Cell Or Subcellular Component DNA Strand Renaturation Arachidonic Acid Secretion Regulation Of Protein Secretion Positive Regulation Of Fatty Acid Biosynthetic Process Adenosine Receptor Signaling Pathway Negative Regulation Of Interleukin-8 Production Regulation Of Interleukin-8 Secretion Inflammatory Response
Tagcloud ?		amplified c5a c5ar chromosomes complement contained digestion electrophoresis filters formylpeptides fpr2 fprl2 fragment homologue hybridized il8ra il8rb kb kilobase library lie linkage mapped nylon probes pulsed restriction separated translated