COMMD3

Description		COMM domain containing 3
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GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding
	Biological Process	Monoatomic Ion Transport Sodium Ion Transport
Pathways		Neutrophil degranulation Neddylation
Drugs
Diseases
GWAS		Prostate-specific antigen levels ( 28139693)
Interacting Genes		4 interacting genes: COMMD1 PIH1D2 TRAF5 ZNF337
Entrez ID		23412
HPRD ID		13082
Ensembl ID		ENSG00000148444
Uniprot IDs		Q9UBI1
PDB IDs		8F2R 8F2U 8P0W
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-binding Transcription Factor Activity R2TP Complex Negative Regulation Of Hypoxia-inducible Factor-1alpha Signaling Pathway Positive Regulation Of Cholesterol Import Regulation Of Cholesterol Import Positive Regulation Of Endosome To Plasma Membrane Protein Transport Regulation Of Plasma Lipoprotein Particle Levels Thioesterase Binding CD40 Receptor Complex CD40 Signaling Pathway Interleukin-17-mediated Signaling Pathway Regulation Of Protein Stability Box C/D SnoRNP Assembly Sodium Channel Inhibitor Activity Positive Regulation Of Endocytic Recycling Plasma Membrane To Endosome Transport Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Cellular Response To Hypoxia Negative Regulation Of Sodium Ion Transport Low-density Lipoprotein Particle Clearance Cul2-RING Ubiquitin Ligase Complex Copper Ion Homeostasis Positive Regulation Of Protein Localization To Cell Surface Regulation Of Endocytic Recycling Regulation Of Cellular Response To Hypoxia Phosphatidic Acid Binding
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