SPIC

Description		Spi-C transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Blastocyst Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 28552196) Lung cancer in never smokers ( 28604730) Lymphocyte count ( 27863252 32888494) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Reticulocyte fraction of red cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		4 interacting genes: APP INTS11 MEOX1 NFE2L2
Entrez ID		121599
HPRD ID		15438
Ensembl ID		ENSG00000166211
Uniprot IDs		Q8N5J4
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Copper Ion Regulation Of Superoxide Metabolic Process Cellular Response To Copper Ion Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Reactive Oxygen Species Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Glutathione Biosynthetic Process Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Catabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Regulation Of Reactive Oxygen Species Metabolic Process Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Metal Ion Low-density Lipoprotein Particle Mediated Signaling Sclerotome Development Proteasomal Ubiquitin-independent Protein Catabolic Process Regulation Of Glutathione Biosynthetic Process Toxin Catabolic Process Negative Regulation Of Hematopoietic Stem Cell Differentiation Aflatoxin Catabolic Process Intermediate-density Lipoprotein Particle Regulation Of DNA-templated Transcription Axon Midline Choice Point Recognition Regulation Of RNA Biosynthetic Process Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Somite Specification Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway
Tagcloud ?