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HNRNPA0 |
heterogeneous nuclear ribonucleoprotein A0 |
- mRNA Splicing - Major Pathway
- Processing of Capped Intron-Containing Pre-mRNA
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HNRNPD |
heterogeneous nuclear ribonucleoprotein D |
- mRNA Splicing - Major Pathway
- Processing of Capped Intron-Containing Pre-mRNA
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HNRNPH3 |
heterogeneous nuclear ribonucleoprotein H3 |
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HSP90AB1 |
heat shock protein 90 alpha family class B member 1 |
- Regulation of actin dynamics for phagocytic cup formation
- HSP90 chaperone cycle for steroid hormone receptors (SHR)
- HSF1 activation
- Attenuation phase
- HSF1-dependent transactivation
- Sema3A PAK dependent Axon repulsion
- Uptake and function of diphtheria toxin
- Neutrophil degranulation
- The NLRP3 inflammasome
- The role of GTSE1 in G2/M progression after G2 checkpoint
- Aryl hydrocarbon receptor signalling
- ESR-mediated signaling
- RHOBTB2 GTPase cycle
- Estrogen-dependent gene expression
- Chaperone Mediated Autophagy
- Purinergic signaling in leishmaniasis infection
- Potential therapeutics for SARS
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- Geldanamycin
- 9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine
- Radicicol
- Tanespimycin
- SNX-5422
- CCT-018159
- 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE
- 4-{4-[4-(3-AMINOPROPOXY)PHENYL]-1H-PYRAZOL-5-YL}-6-CHLOROBENZENE-1,3-DIOL
- (5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE
- (5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE
- (5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE
- (5Z)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONE
- METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE
- 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE
- Polaprezinc
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HSP90B1 |
heat shock protein 90 beta family member 1 |
- Trafficking and processing of endosomal TLR
- Scavenging by Class A Receptors
- Scavenging by Class A Receptors
- ATF6 (ATF6-alpha) activates chaperone genes
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- Interleukin-4 and Interleukin-13 signaling
- Post-translational protein phosphorylation
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- Rifabutin
- 2-Chlorodideoxyadenosine
- Geldanamycin
- Diglyme
- N-Ethyl-5'-Carboxamido Adenosine
- Radicicol
- METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE
- 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE
- Copper
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HSPD1 |
heat shock protein family D (Hsp60) member 1 |
- Mitochondrial protein import
- Mitochondrial protein import
- TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
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- Hereditary spastic paraplegia (SPG)
- Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
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IDH3B |
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta |
- Citric acid cycle (TCA cycle)
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- Retinitis pigmentosa (RP)
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INS |
insulin |
- Regulation of gene expression in beta cells
- Insulin processing
- Insulin processing
- Synthesis, secretion, and deacylation of Ghrelin
- Regulation of insulin secretion
- COPI-mediated anterograde transport
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- IRS activation
- Signal attenuation
- Insulin receptor signalling cascade
- Signaling by Insulin receptor
- Insulin receptor recycling
- FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
- FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
- Amyloid fiber formation
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- Zinc
- M-Cresol
- Myristic acid
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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- Maturity onset diabetes of the young (MODY)
- Type I diabetes mellitus
- Permanent neonatal diabetes mellitus (PNDM)
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ITGB3BP |
integrin subunit beta 3 binding protein |
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- NRIF signals cell death from the nucleus
- NRIF signals cell death from the nucleus
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- RHO GTPases Activate Formins
- Deposition of new CENPA-containing nucleosomes at the centromere
- Mitotic Prometaphase
- EML4 and NUDC in mitotic spindle formation
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ITSN1 |
intersectin 1 |
- NRAGE signals death through JNK
- Rho GTPase cycle
- EPHB-mediated forward signaling
- EPHB-mediated forward signaling
- G alpha (12/13) signalling events
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
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JUNB |
JunB proto-oncogene, AP-1 transcription factor subunit |
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- Interleukin-4 and Interleukin-13 signaling
- NGF-stimulated transcription
- NGF-stimulated transcription
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KDSR |
3-ketodihydrosphingosine reductase |
- Sphingolipid de novo biosynthesis
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KLC1 |
kinesin light chain 1 |
- MHC class II antigen presentation
- RHO GTPases activate KTN1
- COPI-dependent Golgi-to-ER retrograde traffic
- Kinesins
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KNSTRN |
kinetochore localized astrin (SPAG5) binding protein |
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LPXN |
leupaxin |
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MAP3K12 |
mitogen-activated protein kinase kinase kinase 12 |
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MAP3K7 |
mitogen-activated protein kinase kinase kinase 7 |
- Activation of NF-kappaB in B cells
- NOD1/2 Signaling Pathway
- Downstream TCR signaling
- FCERI mediated NF-kB activation
- Ca2+ pathway
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex
- activated TAK1 mediates p38 MAPK activation
- JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
- TNFR1-induced NFkappaB signaling pathway
- CLEC7A (Dectin-1) signaling
- Ub-specific processing proteases
- TICAM1,TRAF6-dependent induction of TAK1 complex
- Interleukin-1 signaling
- IRAK2 mediated activation of TAK1 complex
- TRAF6-mediated induction of TAK1 complex within TLR4 complex
- Alpha-protein kinase 1 signaling pathway
- IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
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MAPKAPK5 |
MAPK activated protein kinase 5 |
- Oxidative Stress Induced Senescence
- MAPK6/MAPK4 signaling
- Regulation of TP53 Activity through Phosphorylation
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MASP1 |
MBL associated serine protease 1 |
- Lectin pathway of complement activation
- Initial triggering of complement
- Ficolins bind to repetitive carbohydrate structures on the target cell surface
- Scavenging by Class A Receptors
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MBIP |
MAP3K12 binding inhibitory protein 1 |
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