IQCB1 and UPK1B

		IQCB1	UPK1B
Description		IQ motif containing B1	uroplakin 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Photoreceptor Connecting Cilium Extracellular Exosome	Membrane Apical Plasma Membrane Extracellular Exosome Apical Plasma Membrane Urothelial Plaque
	Molecular Function	Protein Binding Calmodulin Binding Enzyme Binding Protein-macromolecule Adaptor Activity BBSome Binding	Structural Molecule Activity Protein Binding
	Biological Process	Cell Projection Organization Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Cilium Assembly Cytosolic Ciliogenesis	Response To Bacterium Epithelial Cell Differentiation
Pathways		Anchoring of the basal body to the plasma membrane
Drugs
Diseases		Senior-Loken syndrome
GWAS		Hemoglobin levels ( 32327693) Multiple sclerosis ( 24076602 31604244) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376)	Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
Interacting Genes		18 interacting genes: CALM2 CALML3 CD80 KIF9 LDOC1 LMOD1 MARCHF7 MNS1 NECTIN3 PCMT1 PDE9A SESTD1 SMARCD1 SPG21 TBL1X TRH TRIM32 UPK1B	61 interacting genes: BCL2L13 BEST2 BIK BNIP2 CATSPERH CD53 CD69 CD79A CD80 CERS4 CLDN7 CYB5R3 DAGLA EDAR ERGIC3 FAM209A FFAR2 FKBP7 FNDC9 GJA8 GJB1 GPR161 GPR37L1 GPX8 IQCB1 ISLR2 ITGB2 KASH5 KCNJ6 KIR2DL3 KLRC1 LMNA MFF MS4A4A NEMP1 PDZK1IP1 PIK3IP1 PLPP4 RHCG SAR1A SDHAF4 SHISA4 SIT1 SLC10A1 SLC10A2 SLC16A2 SLC18A1 SLC35H1 SLC39A2 SPINT1 SSMEM1 STX1A SYT9 TMEM139 TMEM237 TMEM45B TMEM54 TMEM91 TMUB2 UPK3A VSIG1
Entrez ID		9657	7348
HPRD ID		11049	03853
Ensembl ID		ENSG00000173226	ENSG00000114638
Uniprot IDs		Q15051	O75841
PDB IDs
Enriched GO Terms of Interacting Partners?		Detection Of Calcium Ion Regulation Of Cilium Assembly Regulation Of Organelle Assembly Calcium Channel Complex Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Calcium Ion Transmembrane Transport Calcineurin-mediated Signaling Myelin Sheath Negative Regulation Of Cell Population Proliferation Regulation Of Organelle Organization Thyrotropin-releasing Hormone Activity Positive Regulation Of Interleukin-17-mediated Signaling Pathway Negative Regulation Of Cilium Assembly Actin Ubiquitination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production	Membrane Protein Binding Plasma Membrane Bile Acid:sodium Symporter Activity
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