SGCE and PDYN

		SGCE	PDYN
Description		sarcoglycan epsilon	prodynorphin
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Membrane Dendrite Dendrite Membrane Sarcolemma Cell Projection	Extracellular Region Plasma Membrane Dendrite Neuronal Cell Body Axon Terminus Hippocampal Mossy Fiber To CA3 Synapse Neuronal Dense Core Vesicle
	Molecular Function		Opioid Peptide Activity Protein Binding Opioid Receptor Binding
	Biological Process	Cell-matrix Adhesion Muscle Organ Development	Neuropeptide Signaling Pathway Chemical Synaptic Transmission Sensory Perception
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)	Opioid Signalling G-protein activation Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases		Primary torsion dystonia (PTD)	Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS			Aortic root size ( 21223598) Immune response to measles-mumps-rubella vaccine ( 24811271) Immune response to smallpox vaccine (IL-6) ( 22542470) Metabolite levels ( 23823483) Platelet count ( 29403010)
Interacting Genes		14 interacting genes: AKAP9 ARIH2 CDK14 CDK6 CWC15 CYP3A7 KEAP1 MED12 MTERF1 PDYN PPP1CC SEMA3C SYT13 TAC1	4 interacting genes: APP NRDC PIGS SGCE
Entrez ID		8910	5173
HPRD ID		04999	08838
Ensembl ID		ENSG00000127990	ENSG00000101327
Uniprot IDs		A0A0S2Z4P5 A0A2R8Y448 A0A2R8Y5J3 A0A2R8YGQ3 B4DP78 C9JR67 E9PEH6 O43556	P01213
PDB IDs			2N2F 7Y1F 8F7W 8VJU 8VJV
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Membrane Protein Ectodomain Proteolysis Dendrite Membrane Regulation Of Membrane Protein Ectodomain Proteolysis Dendrite Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Positive Regulation Of Tumor Necrosis Factor Production Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Regulation Of Nervous System Process Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Proteolysis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Protein Catabolic Process Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Epidermal Growth Factor Binding GPI-anchor Transamidase Complex GPI Anchored Protein Biosynthesis Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Sarcoglycan Complex Attachment Of GPI Anchor To Protein Cell Projection Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity
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