AGPS and KCNH7

		AGPS	KCNH7
Description		alkylglycerone phosphate synthase	potassium voltage-gated channel subfamily H member 7
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane	Plasma Membrane Membrane Monoatomic Ion Channel Complex
	Molecular Function	Catalytic Activity Protein Binding Alkylglycerone-phosphate Synthase Activity Transferase Activity Flavin Adenine Dinucleotide Binding FAD Binding	Monoatomic Ion Channel Activity Inward Rectifier Potassium Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Heme Binding
	Biological Process	Lipid Metabolic Process Lipid Biosynthetic Process Ether Lipid Biosynthetic Process	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Membrane Potential Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Voltage gated Potassium channels
Drugs			Enflurane Ibutilide Amitriptyline Doxazosin Promethazine Miconazole Amiodarone Terazosin Vanoxerine Silodosin
Diseases		Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)
GWAS		Height ( 28552196)	Body fat mass ( 28552196) Breast cancer (survival) ( 25890600) Coronary artery disease ( 29212778) Diabetic kidney disease ( 26305897) General cognitive ability ( 29844566) Inflammatory skin disease ( 25574825) Phospholipid levels (plasma) ( 22359512) Polycystic ovary syndrome (metabolic subtype) ( 32574161) Post bronchodilator FEV1/FVC ratio ( 26634245) Psoriasis ( 23143594) Psoriasis vulgaris ( 26626624) Trunk fat mass ( 28552196) Type 1 diabetes ( 30572963)
Interacting Genes		2 interacting genes: GNPAT GORASP1
Entrez ID		8540	90134
HPRD ID		04337	16295
Ensembl ID		ENSG00000018510	ENSG00000184611
Uniprot IDs		B7Z3Q4 O00116	Q9NS40
PDB IDs			6Y7Q
Enriched GO Terms of Interacting Partners?			Alkylglycerone-phosphate Synthase Activity Ether Lipid Biosynthetic Process Ether Lipid Metabolic Process FAD Binding Peroxisomal Matrix Peroxisomal Membrane Flavin Adenine Dinucleotide Binding Peroxisome Catalytic Activity
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