MS4A14 and CCDC86

		MS4A14	CCDC86
Description		membrane spanning 4-domains A14	coiled-coil domain containing 86
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Nucleoplasm Chromosome Nucleolus
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway	Chromosome Segregation Mitotic Nuclear Division
Pathways
Drugs
Diseases
GWAS		Monocyte count ( 32888494) Post bronchodilator FEV1 ( 26634245)	Wegener's granulomatosis ( 23740775)
Interacting Genes		7 interacting genes: CCDC86 CDIPT CLDN19 GIMAP5 SEC22A TMEM54 TMEM86B	10 interacting genes: AHNAK C9orf153 CPSF7 DLST MS4A14 MS4A15 MS4A8 OGT SRPK2 TUT1
Entrez ID		84689	79080
HPRD ID		14863	08322
Ensembl ID		ENSG00000166928	ENSG00000110104
Uniprot IDs		A0A0A0MS57 Q96JA4	Q9H6F5
PDB IDs			8FL0 8FL2 8FL3 8FL4 8INK 8IPD 8IPX 8IPY 8IR1 8IR3
Enriched GO Terms of Interacting Partners?		CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Alcohol Binding Mesaxon D-lysine 5,6-aminomutase Activity Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Regulation Of Transepithelial Transport Phosphotransferase Activity, For Other Substituted Phosphate Groups Glycerophospholipid Metabolic Process Mitotic Nuclear Division Apical Junction Assembly Schmidt-Lanterman Incisure Paracellular Tight Junction Channel Activity Action Potential Propagation Retinal Pigment Epithelium Development Paracellular Transport Paranodal Junction Neuronal Action Potential Propagation CDP-diacylglycerol Metabolic Process Diacylglycerol Binding Phosphatidylcholine Acyl-chain Remodeling Endoplasmic Reticulum Membrane Glycerolipid Metabolic Process	Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA 3'-end Processing Dihydrolipoyllysine-residue Succinyltransferase Activity Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly
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