GATD3 and GET1

		GATD3	GET1
Description		glutamine amidotransferase class 1 domain containing 3	guided entry of tail-anchored proteins factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex
	Molecular Function	Protein Binding	Protein Binding Protein-membrane Adaptor Activity
	Biological Process		Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Sensory Perception Of Sound Protein Insertion Into ER Membrane Synapse Organization Protein Stabilization Establishment Of Localization In Cell Otic Vesicle Development Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane
Pathways			Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: APP COPS5 FRA10AC1 GET1 PAX6 PJA1 PSMG1 RANBP9 SNRNP70 TAF1	34 interacting genes: ABHD5 APOA2 APOL2 AQP1 BOC CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 GATD3 HMOX2 HTATIP2 ORMDL3 PDXK PLPP4 PTPN9 RASGRP3 RTP2 SCN3A SERP2 SLC35E3 SLC4A2 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42 TRAPPC10
Entrez ID		8209	7485
HPRD ID		09044	04224
Ensembl ID		ENSG00000160221	ENSG00000182093
Uniprot IDs		A0A140VKB0 F2Z2Q0 P0DPI2	O00258
PDB IDs			6SO5 8CQZ 8CR1 8CR2
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Enzyme Binding Regulation Of Response To Calcium Ion Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Amylin Binding Endosome To Plasma Membrane Transport Vesicle Regulation Of Protein Metabolic Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Protein Catabolic Process Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Positive Regulation Of Amyloid Precursor Protein Catabolic Process Nucleus Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Forebrain-midbrain Boundary Formation Pancreatic A Cell Development RNA Polymerase II Core Promoter Sequence-specific DNA Binding Habenula Development Pallium Development Neural Precursor Cell Proliferation Negative Regulation Of Protein Refolding Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Protein Autoubiquitination Positive Regulation Of Androgen Receptor Signaling Pathway GET Complex Proteasome Core Complex Assembly Macrophage Migration Inhibitory Factor Binding Regulation Of Spontaneous Synaptic Transmission Response To Purine-containing Compound Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Central Nervous System Development Intermediate-density Lipoprotein Particle Regulation Of JNK Cascade Axon Midline Choice Point Recognition NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Positive Regulation Of RNA Metabolic Process	Basolateral Plasma Membrane Membrane Serine Palmitoyltransferase Complex
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