PHAF1 and QSOX1

		PHAF1	QSOX1
Description		phagophore assembly factor 1	quiescin sulfhydryl oxidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Cytoplasm Trans-Golgi Network Dendrite Synaptic Vesicle Membrane	Golgi Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Membrane Platelet Alpha Granule Lumen Specific Granule Lumen Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	Protein Binding	Protein Disulfide Isomerase Activity Oxidoreductase Activity Flavin-dependent Sulfhydryl Oxidase Activity Thiol Oxidase Activity FAD Binding
	Biological Process	Golgi To Plasma Membrane Protein Transport	Protein Folding Negative Regulation Of Macroautophagy Extracellular Matrix Assembly
Pathways			Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS			Anorexia nervosa ( 23568457) Pulse pressure ( 30224653 30578418)
Interacting Genes		10 interacting genes: APP ATXN3 CBFA2T2 CCDC102B KIF17 MPPED1 NPBWR2 PRR5L TOLLIP TSHZ2	7 interacting genes: BEGAIN CCR1 CCR6 CHRM4 SHANK3 UBE2D2 UBQLN4
Entrez ID		80262	5768
HPRD ID		17460	06785
Ensembl ID		ENSG00000125149	ENSG00000116260
Uniprot IDs		Q9BSU1	A0A140VKE5 O00391
PDB IDs			3LLI 3LLK 3Q6O 4IJ3
Enriched GO Terms of Interacting Partners?			G Protein-coupled Receptor Activity Chemokine Receptor Activity Dendritic Cell Migration Dendritic Cell Chemotaxis C-C Chemokine Binding C-C Chemokine Receptor Activity Positive Regulation Of Synaptic Transmission Regulation Of Neuron Projection Regeneration Positive Regulation Of Synaptic Transmission, Glutamatergic
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