ARMC5 and DCTPP1

		ARMC5	DCTPP1
Description		armadillo repeat containing 5	dCTP pyrophosphatase 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Focal Adhesion Membrane Cul3-RING Ubiquitin Ligase Complex	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Nucleotide Binding Magnesium Ion Binding Protein Binding Pyrophosphatase Activity Hydrolase Activity Pyrimidine Deoxyribonucleotide Binding Identical Protein Binding Metal Ion Binding Nucleoside Triphosphate Diphosphatase Activity DCTP Diphosphatase Activity
	Biological Process	In Utero Embryonic Development Mesoderm Formation Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Gastrulation Anatomical Structure Morphogenesis Hemopoiesis Adrenal Cortex Development T Cell Proliferation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process CD4-positive, Alpha-beta T Cell Differentiation Regulation Of Steroid Biosynthetic Process Defense Response To Virus RNA Polymerase II Transcription Initiation Surveillance	DCTP Catabolic Process Nucleoside Triphosphate Catabolic Process DNA Protection DTTP Catabolic Process
Pathways			Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS			Urinary sodium excretion ( 31409800)
Interacting Genes		11 interacting genes: CNOT2 COL8A1 DCTPP1 ENKD1 GLYCTK MKRN3 PRR35 SPAG8 TLX3 USHBP1 USP7	22 interacting genes: APP ARMC5 FMR1 FXR1 FXR2 GDPD3 LNX1 NIF3L1 NOA1 NTAQ1 PAGR1 PRR14 PSMA1 RUSF1 SDCBP SLX1B SPG21 USP7 VKORC1 ZNF668 ZNF747 ZNF768
Entrez ID		79798	79077
HPRD ID		07809	18310
Ensembl ID		ENSG00000140691	ENSG00000179958
Uniprot IDs		B4DH27 B4DIU9 J3KQ26 Q96C12	Q9H773
PDB IDs			7MU5
Enriched GO Terms of Interacting Partners?			Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Translation Regulator Activity Growth Cone Filopodium Postsynapse RNA Strand Annealing Activity Presynaptic Modulation Of Chemical Synaptic Transmission Intracellular Membraneless Organelle Protein Heterodimerization Activity Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing Regulation Of Synaptic Plasticity Regulation Of Receptor Internalization Cytoplasmic Ribonucleoprotein Granule Presynapse Collateral Sprouting Cytoplasmic Stress Granule DNA Repair Positive Regulation Of Catabolic Process Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization MRNA Transport MRNA 3'-UTR Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Dentate Gyrus Development Neuron Maturation Regulation Of Nucleobase-containing Compound Metabolic Process Neuron Projection Frizzled Binding Dendritic Spine RNA Transport Positive Regulation Of Translation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Intracellular Transport Of Viral Material Interleukin-5 Receptor Complex Protein-N-terminal Glutamine Amidohydrolase Activity Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Adrenal Cortex Development Regulation Of Long-term Synaptic Potentiation Chromosome Regulation Of RNA Metabolic Process Regulation Of Translation Molecular Condensate Scaffold Activity
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