THTPA and METTL17

		THTPA	METTL17
Description		thiamine triphosphatase	methyltransferase like 17
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleoplasm Mitochondrion Mitochondrial Matrix Intracellular Organelle Lumen
	Molecular Function	Magnesium Ion Binding Protein Binding Hydrolase Activity Metal Ion Binding Thiamine Triphosphate Phosphatase Activity	Protein Binding Methyltransferase Activity Small Molecule Binding Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding Mitochondrial Ribosome Binding S-adenosyl-L-methionine Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Thiamine Metabolic Process Phosphate-containing Compound Metabolic Process Thiamine Diphosphate Biosynthetic Process Dephosphorylation Thiamine Diphosphate Metabolic Process Thiamine-containing Compound Metabolic Process	Translation Ribosomal Small Subunit Biogenesis Mitochondrial Small Ribosomal Subunit Assembly
Pathways		Vitamin B1 (thiamin) metabolism
Drugs
Diseases
GWAS			Degraded stimulus continuous performance test score ( 31596458)
Interacting Genes		1 interacting genes: TLX3	21 interacting genes: ATXN1 ATXN1L CALCOCO2 CARD10 CBY2 CEP70 KRT34 KRT40 MAPK6 MDFI MEOX2 MID2 MTUS2 NUDT16L1 NUTM1 PNMA1 SF3B4 TFIP11 TRAF1 TRIP6 VCP
Entrez ID		79178	64745
HPRD ID		15505	13379
Ensembl ID		ENSG00000259431	ENSG00000165792
Uniprot IDs		G3V5Q5 Q9BU02	A0A0S2Z5L8 Q9H7H0
PDB IDs		3BHD 3TVL	8CSP 8CSQ 8CSR 8CSS 8CST 8CSU
Enriched GO Terms of Interacting Partners?			POZ Domain Binding Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
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