DCTPP1 and ARMC5

		DCTPP1	ARMC5
Description		dCTP pyrophosphatase 1	armadillo repeat containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol	Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Focal Adhesion Membrane Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Binding Pyrophosphatase Activity Hydrolase Activity Pyrimidine Deoxyribonucleotide Binding Identical Protein Binding Metal Ion Binding Nucleoside Triphosphate Diphosphatase Activity DCTP Diphosphatase Activity	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	DCTP Catabolic Process Nucleoside Triphosphate Catabolic Process DNA Protection DTTP Catabolic Process	In Utero Embryonic Development Mesoderm Formation Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Gastrulation Anatomical Structure Morphogenesis Hemopoiesis Adrenal Cortex Development T Cell Proliferation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process CD4-positive, Alpha-beta T Cell Differentiation Regulation Of Steroid Biosynthetic Process Defense Response To Virus RNA Polymerase II Transcription Initiation Surveillance
Pathways		Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Urinary sodium excretion ( 31409800)
Interacting Genes		22 interacting genes: APP ARMC5 FMR1 FXR1 FXR2 GDPD3 LNX1 NIF3L1 NOA1 NTAQ1 PAGR1 PRR14 PSMA1 RUSF1 SDCBP SLX1B SPG21 USP7 VKORC1 ZNF668 ZNF747 ZNF768	11 interacting genes: CNOT2 COL8A1 DCTPP1 ENKD1 GLYCTK MKRN3 PRR35 SPAG8 TLX3 USHBP1 USP7
Entrez ID		79077	79798
HPRD ID		18310	07809
Ensembl ID		ENSG00000179958	ENSG00000140691
Uniprot IDs		Q9H773	B4DH27 B4DIU9 J3KQ26 Q96C12
PDB IDs		7MU5
Enriched GO Terms of Interacting Partners?		Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Translation Regulator Activity Growth Cone Filopodium Postsynapse RNA Strand Annealing Activity Presynaptic Modulation Of Chemical Synaptic Transmission Intracellular Membraneless Organelle Protein Heterodimerization Activity Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing Regulation Of Synaptic Plasticity Regulation Of Receptor Internalization Cytoplasmic Ribonucleoprotein Granule Presynapse Collateral Sprouting Cytoplasmic Stress Granule DNA Repair Positive Regulation Of Catabolic Process Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization MRNA Transport MRNA 3'-UTR Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Dentate Gyrus Development Neuron Maturation Regulation Of Nucleobase-containing Compound Metabolic Process Neuron Projection Frizzled Binding Dendritic Spine RNA Transport Positive Regulation Of Translation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Intracellular Transport Of Viral Material Interleukin-5 Receptor Complex Protein-N-terminal Glutamine Amidohydrolase Activity Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Adrenal Cortex Development Regulation Of Long-term Synaptic Potentiation Chromosome Regulation Of RNA Metabolic Process Regulation Of Translation Molecular Condensate Scaffold Activity
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