MRPS11 and MFGE8

		MRPS11	MFGE8
Description		mitochondrial ribosomal protein S11	milk fat globule EGF and factor V/VIII domain containing
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex	Acrosomal Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen External Side Of Plasma Membrane Membrane Extracellular Matrix Cytoplasmic Vesicle Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Phosphatidylserine Binding Integrin Binding Extracellular Matrix Structural Constituent
	Biological Process	Translation Mitochondrial Translation	Angiogenesis Cell Adhesion Single Fertilization Apoptotic Cell Clearance
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Amyloid fiber formation Developmental Lineage of Mammary Gland Alveolar Cells
Drugs
Diseases
GWAS		Familial hepatitis B virus-related hepatocellular carcinoma ( 28662289)	Blood protein levels ( 30072576) Coronary artery disease ( 26343387 32469254 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Liver enzyme levels (alkaline phosphatase) ( 33972514) Major depressive disorder x sex interaction ( 34099189) Pulse pressure ( 27841878) Serum alkaline phosphatase levels ( 33547301) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		5 interacting genes: KRT31 MFGE8 NAA10 PRPF6 SRPK1	8 interacting genes: LOXL1 MRPL46 MRPS11 PRLR PSTPIP1 RSPH1 TM6SF1 TRIP13
Entrez ID		64963	4240
HPRD ID		14776	03789
Ensembl ID		ENSG00000181991	ENSG00000140545
Uniprot IDs		P82912	A0A8Q3SIZ9 B3KTQ2 B4E396 H0YKB5 Q08431
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?		Spliceosomal Complex Assembly Protein-N-terminal-alanine Acetyltransferase Activity Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Protein N-terminal-serine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Protein-RNA Complex Assembly Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Sister Chromatid Cohesion NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity Internal Protein Amino Acid Acetylation N-terminal Protein Amino Acid Acetylation RNA Splicing N-acetyltransferase Activity Nuclear Speck Sperm DNA Condensation Regulation Of Sister Chromatid Cohesion Acetyltransferase Activity Spliceosomal Tri-snRNP Complex Assembly U5 SnRNP MRNA Processing
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