ADGRB2 and B4GALT2

		ADGRB2	B4GALT2
Description		adhesion G protein-coupled receptor B2	beta-1,4-galactosyltransferase 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Synapse Glutamatergic Synapse	Golgi Membrane Nucleoplasm Golgi Apparatus Membrane Golgi Cisterna Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding	Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity N-acetyllactosamine Synthase Activity Lactose Synthase Activity Protein Binding Galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity Metal Ion Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Peripheral Nervous System Development Negative Regulation Of Angiogenesis Calcineurin-NFAT Signaling Cascade Positive Regulation Of Synapse Assembly	Carbohydrate Metabolic Process Protein Glycosylation Brain Development Memory Locomotory Behavior Visual Learning Cerebellar Purkinje Cell Layer Development Glycosylation
Pathways			Keratan sulfate biosynthesis N-Glycan antennae elongation
Drugs
Diseases
GWAS		Asthma ( 31959851) Intraocular pressure ( 29617998 29785010) Smoking status (ever vs never smokers) ( 30643258) Walking pace ( 33128006)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576)
Interacting Genes		11 interacting genes: ARHGAP1 B4GALT2 DLG4 GABPB1 HDAC5 HDHD2 LRP2BP SHANK1 SHANK2 SNTA1 STARD13	13 interacting genes: ADGRB2 DES GPR35 GUCA2B ITSN2 KLK13 MAGOH MATN1 MEOX2 PFDN6 SLC39A14 TRIM63 USO1
Entrez ID		576	8704
HPRD ID		04063	04928
Ensembl ID		ENSG00000121753	ENSG00000117411
Uniprot IDs		A2A3C1 O60241	O60909
PDB IDs		8OEK
Enriched GO Terms of Interacting Partners?		Vocalization Behavior Ionotropic Glutamate Receptor Binding Learning Synaptic Receptor Adaptor Activity Social Behavior Learning Or Memory Associative Learning Cognition SH3 Domain Binding Dendritic Spine Morphogenesis Dendritic Spine Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Ionotropic Glutamate Receptor Signaling Pathway Excitatory Synapse Positive Regulation Of Excitatory Postsynaptic Potential Dendritic Spine Organization Ligand-gated Ion Channel Signaling Pathway Neuron Projection Organization Postsynapse Organization Postsynaptic Membrane Neuromuscular Process Controlling Balance Modulation Of Excitatory Postsynaptic Potential Glutamate Receptor Signaling Pathway Postsynaptic Density Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis P2Y1 Nucleotide Receptor Binding Protein Localization To Synapse Determination Of Affect Somatostatin Receptor Binding Scaffold Protein Binding Negative Regulation Of Endothelial Cell Migration Neuron Projection Neuromuscular Junction Protein Localization To Cell Junction PDZ Domain Binding Endothelial Tube Lumen Extension System Process Negative Regulation Of Endocytic Recycling Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Nervous System Process Lactose Synthase Activity Structural Constituent Of Postsynaptic Density Regulation Of Nervous System Process Regulation Of Membrane Potential Neuromuscular Process Syntrophin Complex N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity	Contractile Muscle Fiber
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