PSMB9 and NDUFB9

		PSMB9	NDUFB9
Description		proteasome 20S subunit beta 9	NADH:ubiquinone oxidoreductase subunit B9
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GO Annotations	Cellular Component	Proteasome Complex Nucleus Cytoplasm Cytosol Proteasome Core Complex Proteasome Core Complex, Beta-subunit Complex Extracellular Exosome Spermatoproteasome Complex	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I
	Molecular Function	Endopeptidase Activity Threonine-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Immune System Process Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process	Mitochondrial Electron Transport, NADH To Ubiquinone Sensory Perception Of Sound Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		ER-Phagosome pathway Cross-presentation of soluble exogenous antigens (endosomes) Proteasome assembly Proteasome assembly Antigen processing: Ub, ATP-independent proteasomal degradation	Respiratory electron transport Complex I biogenesis
Drugs		Carfilzomib	NADH
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 23266558) Disc degeneration (lumbar) ( 22993228) Hip circumference adjusted for BMI ( 34021172) IgA nephropathy ( 25305756) Nephropathy ( 21399633) Platelet distribution width ( 27863252) Rosacea symptom severity ( 29771307) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Systemic lupus erythematosus ( 32771030)
Interacting Genes		12 interacting genes: BRD2 CRYGA DDIT4L DYNC1H1 LAGE3 NCOA1 NCOA2 NCOA3 NDUFB9 POMP PSMB10 PTK7	20 interacting genes: DRC7 ELP1 EYA1 FEZ1 GDF9 HAP1 IMMT MAGEA11 MEF2A MYCBP2 OR2D2 PRDM14 PRPF31 PSMB9 RAD54B RBBP6 SH3GL3 TNIP2 UBC XRN1
Entrez ID		5698	4715
HPRD ID		01514	03264
Ensembl ID		ENSG00000240065	ENSG00000147684
Uniprot IDs		A0A1U9X8D7 P28065	E9PH64 Q9Y6M9
PDB IDs		6AVO 6E5B 7AWE 7B12 9FST	5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Cellular Response To Thyroglobulin Triiodothyronine Nuclear Receptor Binding Response To Thyroglobulin Triiodothyronine Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Adipose Tissue Development Nuclear Receptor-mediated Signaling Pathway Regulation Of Adipose Tissue Development Protein-lysine-acetyltransferase Activity Protein Dimerization Activity Histone Acetyltransferase Activity Response To Progesterone Intracellular Receptor Signaling Pathway MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose MRNA Transcription Transcription Coactivator Activity Histone H4K5ac Reader Activity Histone H4K12ac Reader Activity Acetylation-dependent Protein Binding Labyrinthine Layer Morphogenesis Regulation Of Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Neural Tube Closure Tube Closure Response To Lipid Positive Regulation Of Female Receptivity Response To Retinoic Acid Histone H3K14ac Reader Activity Response To Estradiol Vitamin D Receptor Signaling Pathway	Mitochondrion Localization Regulation Of Organelle Transport Along Microtubule Regulation Of Microtubule-based Movement Mitochondrion Distribution
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