PRRG2 and RTN4RL1

		PRRG2	RTN4RL1
Description		proline rich and Gla domain 2	reticulon 4 receptor like 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane	Extracellular Region Plasma Membrane Cell Surface Membrane Cell Projection Perikaryon Membrane Raft Extracellular Exosome Side Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Calcium Ion Binding Protein Binding	Protein Binding Heparin Binding Chondroitin Sulfate Binding Signaling Receptor Activity
	Biological Process	Proteolysis Blood Coagulation	Negative Regulation Of Neuron Projection Development Corpus Callosum Development Axon Regeneration Negative Regulation Of Axon Regeneration Positive Regulation Of Synapse Assembly
Pathways			Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Hematocrit ( 27863252 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Iron status biomarkers (total iron binding capacity) ( 33536631) Red blood cell count ( 27863252 32888494) Schizophrenia ( 25056061 29483656 30285260)	Adult body size ( 32376654) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Bipolar disorder ( 31043756 34002096) Body mass index ( 31888951) Brain morphology (MOSTest) ( 32665545) Diisocyanate-induced asthma ( 25918132) Fasting glucose ( 33381925) Sulfasalazine-induced agranulocytosis ( 28762467) Type 2 diabetes ( 29621232) Walking pace ( 33128006)
Interacting Genes		14 interacting genes: CCL4 CRK CYTH2 FAM221A FATE1 NEDD4 NEDD4L NKG7 PPP2R1A RTN4RL1 SGTA SNX15 WWTR1 YAP1	9 interacting genes: CYSRT1 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 NBPF19 NOTCH2NLA OMG PRRG2
Entrez ID		5639	146760
HPRD ID		09189	11523
Ensembl ID		ENSG00000126460	ENSG00000185924
Uniprot IDs		O14669 Q8TAS3	Q86UN2
PDB IDs		9BVP 9BVQ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Sodium Channel Inhibitor Activity Regulation Of Potassium Ion Export Across Plasma Membrane Potassium Channel Inhibitor Activity Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Dendrite Development Negative Regulation Of Sodium Ion Transport Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Proline-rich Region Binding Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Receptor Catabolic Process Negative Regulation Of Potassium Ion Transmembrane Transport Bicellular Tight Junction Hippo Signaling Positive Regulation Of Cell Growth Negative Regulation Of Potassium Ion Transport Heart Process Regulation Of Neuron Projection Development Neuromuscular Junction Development Plasma Membrane Bounded Cell Projection Organization Neuron Projection Development Plasma Membrane Positive Regulation Of Protein Catabolic Process Receptor Metabolic Process Formation Of Structure Involved In A Symbiotic Process Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Meiotic Spindle Elongation Enterocyte Differentiation Protein Monoubiquitination Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Growth Macromolecule Catabolic Process Mesenchyme Development Regulation Of Growth Regulation Of Dendrite Morphogenesis Helper T Cell Diapedesis Regulation Of Lymphocyte Migration Protein Phosphorylated Amino Acid Binding Cell Projection Organization Response To Cholecystokinin Regulation Of Developmental Process Receptor Internalization Channel Inhibitor Activity Negative Regulation Of Cation Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Sodium Ion Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Meiotic Cell Cycle Process Involved In Oocyte Maturation	Keratin Filament Intermediate Filament
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