FBXL12 and ZNF562

		FBXL12	ZNF562
Description		F-box and leucine rich repeat protein 12	zinc finger protein 562
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Cytosol	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Generic Transcription Pathway
Drugs
Diseases
GWAS		Pursuit maintenance gain ( 29064472)
Interacting Genes		19 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FBF1 FXYD3 GEMIN4 LNX1 MAST1 PSEN1 PSEN2 PSME3 RNF32 SMAD1 TGFBR1 UBE2D3
Entrez ID		54850	54811
HPRD ID		12363	15844
Ensembl ID		ENSG00000127452	ENSG00000171466
Uniprot IDs		Q9NXK8	B4DMG0 B4E2P7 K7EIE6 Q6V9R5
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid Precursor Protein Metabolic Process Positive Regulation Of Amyloid Fibril Formation Aspartic Endopeptidase Activity, Intramembrane Cleaving Gamma-secretase Complex Notch Receptor Processing Amyloid-beta Formation Regulation Of Amyloid Fibril Formation I-SMAD Binding Amyloid Precursor Protein Catabolic Process
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