VPS13C and LDHAL6B

		VPS13C	LDHAL6B
Description		vacuolar protein sorting 13 homolog C	lactate dehydrogenase A like 6B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Lysosome Lysosomal Membrane Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Membrane Late Endosome Membrane Dense Core Granule Membrane Extracellular Exosome	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Oxidoreductase Complex
	Molecular Function		Catalytic Activity L-lactate Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	Protein Targeting To Vacuole Lipid Transport Golgi To Endosome Transport Mitochondrion Organization Response To Insulin Protein Retention In Golgi Apparatus Negative Regulation Of Type 2 Mitophagy	Lactate Metabolic Process Carboxylic Acid Metabolic Process Pyruvate Catabolic Process
Pathways			Pyruvate metabolism
Drugs			NADH
Diseases
GWAS		Asthma ( 29273806) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Body mass index ( 28892062) Breast size ( 27182965) Cataracts ( 34127677) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Fasting blood proinsulin levels ( 23263489) Glaucoma (primary open-angle) ( 33627673 29891935) HDL cholesterol levels ( 32203549) Insular cortex volume ( 31530798) Intraocular pressure ( 29785010 31959993 30054594) Parkinson's disease ( 28892059 25064009) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Proinsulin levels ( 21873549) Schizophrenia ( 29483656 28991256) Triglyceride levels ( 32203549) Tuberculosis susceptibility in HIV infection ( 26942285) Two-hour glucose ( 34059833) Two-hour glucose challenge ( 20081857)
Interacting Genes		4 interacting genes: LDHAL6B RAB8B SNCA TMEM132D	7 interacting genes: APPL2 HSH2D PRMT5 PRMT6 SOCS4 SUV39H1 VPS13C
Entrez ID		54832	92483
HPRD ID		12323	13981
Ensembl ID		ENSG00000129003	ENSG00000171989
Uniprot IDs		Q709C8	A0A140VJM9 Q9BYZ2
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Synaptic Vesicle Negative Regulation Of Dopamine Metabolic Process Presynapse Negative Regulation Of Serotonin Uptake Regulation Of Chaperone-mediated Autophagy Transporter Regulator Activity Exocytosis Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Catecholamine Metabolic Process Response To Iron(II) Ion Negative Regulation Of Chaperone-mediated Autophagy Regulation Of Serotonin Uptake Positive Regulation Of Secretion By Cell Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Oxidative Phosphorylation Protein Import Into Peroxisome Membrane Positive Regulation Of Corticotropin Secretion Regulation Of Corticotropin Secretion TPR Domain Binding Cell Tip Pyruvate Catabolic Process L-lactate Dehydrogenase (NAD+) Activity Oxidoreductase Complex Mitochondrial ATP Synthesis Coupled Electron Transport Positive Regulation Of Secretion Cuprous Ion Binding Dopamine Biosynthetic Process Negative Regulation Of Cellular Respiration Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber Catecholamine Uptake Dopamine Uptake Positive Regulation Of Inositol Phosphate Biosynthetic Process SNARE Complex Assembly Cellular Response To Epinephrine Stimulus Positive Regulation Of Neurotransmitter Secretion Regulation Of SNARE Complex Assembly Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of Microtubule Polymerization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway ATP Synthesis Coupled Electron Transport	Histone H3 Methyltransferase Activity Histone Methyltransferase Activity Histone Arginine N-methyltransferase Activity Histone H4R3 Methyltransferase Activity Protein-arginine N-methyltransferase Activity Methyltransferase Activity Methylation Negative Regulation Of Metabolic Process Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Histone H2AR3 Methyltransferase Activity Positive Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Peptidyl-arginine N-methylation Dense Core Granule Membrane Negative Regulation Of Type 2 Mitophagy Histone H3R2 Methyltransferase Activity Positive Regulation Of Macropinocytosis ENoSc Complex Negative Regulation Of Macromolecule Metabolic Process Circadian Rhythm Protein-arginine Omega-N Symmetric Methyltransferase Activity Regulation Of Signal Transduction By P53 Class Mediator Early Phagosome Membrane Cold Acclimation Regulation Of Multicellular Organismal Development Histone H3K9 Trimethyltransferase Activity Negative Regulation Of Gene Expression, Epigenetic Chromatin Remodeling RDNA Heterochromatin Positive Regulation Of Dopamine Receptor Signaling Pathway Peptidyl-arginine Methylation Protein Retention In Golgi Apparatus Protein-arginine Omega-N Monomethyltransferase Activity Macropinosome Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway RDNA Heterochromatin Formation Protein-arginine Omega-N Asymmetric Methyltransferase Activity Positive Regulation Of Pinocytosis Histone H3K9me2 Methyltransferase Activity Regulation Of Transcription By Glucose Chromatin Organization Regulation Of Cell Development Adiponectin-activated Signaling Pathway Negative Regulation Of Mitochondrial Depolarization Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Histone H3K9 Methyltransferase Activity Golgi Ribbon Formation Endothelial Cell Activation Diet Induced Thermogenesis Nuclear Lamina
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?