PDYN and SGCE

		PDYN	SGCE
Description		prodynorphin	sarcoglycan epsilon
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Dendrite Neuronal Cell Body Axon Terminus Hippocampal Mossy Fiber To CA3 Synapse Neuronal Dense Core Vesicle	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Membrane Dendrite Dendrite Membrane Sarcolemma Cell Projection
	Molecular Function	Opioid Peptide Activity Protein Binding Opioid Receptor Binding
	Biological Process	Neuropeptide Signaling Pathway Chemical Synaptic Transmission Sensory Perception	Cell-matrix Adhesion Muscle Organ Development
Pathways		Opioid Signalling G-protein activation Peptide ligand-binding receptors G alpha (i) signalling events	Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)	Primary torsion dystonia (PTD)
GWAS		Aortic root size ( 21223598) Immune response to measles-mumps-rubella vaccine ( 24811271) Immune response to smallpox vaccine (IL-6) ( 22542470) Metabolite levels ( 23823483) Platelet count ( 29403010)
Interacting Genes		4 interacting genes: APP NRDC PIGS SGCE	14 interacting genes: AKAP9 ARIH2 CDK14 CDK6 CWC15 CYP3A7 KEAP1 MED12 MTERF1 PDYN PPP1CC SEMA3C SYT13 TAC1
Entrez ID		5173	8910
HPRD ID		08838	04999
Ensembl ID		ENSG00000101327	ENSG00000127990
Uniprot IDs		P01213	A0A0S2Z4P5 A0A2R8Y448 A0A2R8Y5J3 A0A2R8YGQ3 B4DP78 C9JR67 E9PEH6 O43556
PDB IDs		2N2F 7Y1F 8F7W 8VJU 8VJV
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Membrane Protein Ectodomain Proteolysis Dendrite Membrane Regulation Of Membrane Protein Ectodomain Proteolysis Dendrite Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Positive Regulation Of Tumor Necrosis Factor Production Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Regulation Of Nervous System Process Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Proteolysis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Protein Catabolic Process Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Epidermal Growth Factor Binding GPI-anchor Transamidase Complex GPI Anchored Protein Biosynthesis Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Sarcoglycan Complex Attachment Of GPI Anchor To Protein Cell Projection Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity
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