MX2 and NDUFV3

		MX2	NDUFV3
Description		MX dynamin like GTPase 2	NADH:ubiquinone oxidoreductase subunit V3
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Cytoplasm Cytosol Microtubule Plasma Membrane Synapse Presynapse	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding	RNA Binding Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Immune System Process Defense Response Response To Virus Protein Transport Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Response To Interferon-alpha Innate Immune Response Regulation Of Nucleocytoplasmic Transport MRNA Transport Defense Response To Virus Regulation Of Cell Cycle	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Mitochondrial ATP Synthesis Coupled Electron Transport Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	Respiratory electron transport Complex I biogenesis Mitochondrial protein degradation
Drugs			NADH Ubidecarenone
Diseases
GWAS		Cutaneous malignant melanoma ( 32341527) Melanoma ( 21983787 28212542) Nevus count or cutaneous melanoma ( 30429480 32341527) Parkinson disease and lewy body pathology ( 25663231) Tau burden ( 33426524)
Interacting Genes		3 interacting genes: ATRIP EHMT2 PIAS2	2 interacting genes: PHYHIP PTBP1
Entrez ID		4600	4731
HPRD ID		01001	03716
Ensembl ID		ENSG00000183486	ENSG00000160194
Uniprot IDs		P20592	P56181
PDB IDs		4WHJ 4X0R 5UOT	5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?			Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Vesicle Budding From Membrane Microtubule Poly-pyrimidine Tract Binding
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