MX2 and STK38L

		MX2	STK38L
Description		MX dynamin like GTPase 2	serine/threonine kinase 38 like
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Cytoplasm Cytosol Microtubule Plasma Membrane Synapse Presynapse	Cytoplasm Cytosol Cytoskeleton Actin Cytoskeleton Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding	Nucleotide Binding Magnesium Ion Binding Actin Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Immune System Process Defense Response Response To Virus Protein Transport Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Response To Interferon-alpha Innate Immune Response Regulation Of Nucleocytoplasmic Transport MRNA Transport Defense Response To Virus Regulation Of Cell Cycle	Protein Phosphorylation Negative Regulation Of Metabolic Process Negative Regulation Of Autophagy Positive Regulation Of Autophagy Intracellular Signal Transduction Regulation Of Cellular Component Organization
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs			Fostamatinib
Diseases
GWAS		Cutaneous malignant melanoma ( 32341527) Melanoma ( 21983787 28212542) Nevus count or cutaneous melanoma ( 30429480 32341527) Parkinson disease and lewy body pathology ( 25663231) Tau burden ( 33426524)	Diastolic blood pressure ( 30224653) Glioma ( 30714141) Mean platelet volume ( 32888494)
Interacting Genes		3 interacting genes: ATRIP EHMT2 PIAS2	2 interacting genes: STK24 YWHAB
Entrez ID		4600	23012
HPRD ID		01001	10256
Ensembl ID		ENSG00000183486	ENSG00000211455
Uniprot IDs		P20592	Q9Y2H1
PDB IDs		4WHJ 4X0R 5UOT	5XQZ
Enriched GO Terms of Interacting Partners?			Regulation Of Nucleocytoplasmic Transport Regulation Of Intracellular Transport Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Cadherin Binding Phosphoserine Residue Binding
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