MFGE8 and MRPS11

		MFGE8	MRPS11
Description		milk fat globule EGF and factor V/VIII domain containing	mitochondrial ribosomal protein S11
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen External Side Of Plasma Membrane Membrane Extracellular Matrix Cytoplasmic Vesicle Extracellular Exosome Extracellular Vesicle	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	Phosphatidylserine Binding Integrin Binding Extracellular Matrix Structural Constituent	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Angiogenesis Cell Adhesion Single Fertilization Apoptotic Cell Clearance	Translation Mitochondrial Translation
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Amyloid fiber formation Developmental Lineage of Mammary Gland Alveolar Cells	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Coronary artery disease ( 26343387 32469254 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Liver enzyme levels (alkaline phosphatase) ( 33972514) Major depressive disorder x sex interaction ( 34099189) Pulse pressure ( 27841878) Serum alkaline phosphatase levels ( 33547301) Squamous cell lung carcinoma ( 28604730)	Familial hepatitis B virus-related hepatocellular carcinoma ( 28662289)
Interacting Genes		8 interacting genes: LOXL1 MRPL46 MRPS11 PRLR PSTPIP1 RSPH1 TM6SF1 TRIP13	5 interacting genes: KRT31 MFGE8 NAA10 PRPF6 SRPK1
Entrez ID		4240	64963
HPRD ID		03789	14776
Ensembl ID		ENSG00000140545	ENSG00000181991
Uniprot IDs		A0A8Q3SIZ9 B3KTQ2 B4E396 H0YKB5 Q08431	P82912
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?			Spliceosomal Complex Assembly Protein-N-terminal-alanine Acetyltransferase Activity Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Protein N-terminal-serine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Protein-RNA Complex Assembly Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Sister Chromatid Cohesion NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity Internal Protein Amino Acid Acetylation N-terminal Protein Amino Acid Acetylation RNA Splicing N-acetyltransferase Activity Nuclear Speck Sperm DNA Condensation Regulation Of Sister Chromatid Cohesion Acetyltransferase Activity Spliceosomal Tri-snRNP Complex Assembly U5 SnRNP MRNA Processing
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