LY6E and GPAA1

		LY6E	GPAA1
Description		lymphocyte antigen 6 family member E	glycosylphosphatidylinositol anchor attachment 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Synapse Side Of Membrane	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Membrane GPI-anchor Transamidase Complex
	Molecular Function	Protein Binding Acetylcholine Receptor Inhibitor Activity Acetylcholine Receptor Binding	GPI-anchor Transamidase Activity Protein Binding GPI Anchor Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Host-mediated Suppression Of Symbiont Invasion Acetylcholine Receptor Signaling Pathway	GPI Anchor Biosynthetic Process Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS			Asthma ( 31959851) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 23093944)
Interacting Genes		14 interacting genes: AKR1B1 CD247 EIF3H FCGR2B GLI4 GML GPAA1 HSF1 JRK MFSD6 PIP TMEM140 TMEM19 TRARG1	19 interacting genes: ADAMDEC1 AGTR1 AQP2 CACNG8 DGAT1 EIF3E GIT1 GNRHR GRIK5 LRRC14 LY6E NDRG1 PIGK PIGT PIGU PIN1 PRR13 TERF2IP TONSL
Entrez ID		4061	8733
HPRD ID		03227	04334
Ensembl ID		ENSG00000160932	ENSG00000197858
Uniprot IDs		Q16553	O43292
PDB IDs			7W72 7WLD 8IMX 8IMY
Enriched GO Terms of Interacting Partners?		IgG Binding	GPI-anchor Transamidase Complex GPI Anchored Protein Biosynthesis Attachment Of GPI Anchor To Protein GPI Anchor Binding GPI-anchor Transamidase Activity GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Glycolipid Biosynthetic Process Glycolipid Metabolic Process Phosphatidylinositol Biosynthetic Process Glycerolipid Metabolic Process Phosphatidylinositol Metabolic Process Gamma-tubulin Binding Glycerophospholipid Biosynthetic Process Angiotensin Type I Receptor Activity Cis-trans Isomerase Activity Negative Regulation Of ARF Protein Signal Transduction Membrane Lipid Metabolic Process
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