LY6E and PIP

		LY6E	PIP
Description		lymphocyte antigen 6 family member E	prolactin induced protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Synapse Side Of Membrane	Extracellular Region Extracellular Space Nucleus Extracellular Exosome
	Molecular Function	Protein Binding Acetylcholine Receptor Inhibitor Activity Acetylcholine Receptor Binding	Actin Binding Aspartic-type Endopeptidase Activity Protein Binding IgG Binding Identical Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Host-mediated Suppression Of Symbiont Invasion Acetylcholine Receptor Signaling Pathway	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Regulation Of Immune System Process Proteolysis Positive Regulation Of Gene Expression Negative Regulation Of T Cell Apoptotic Process
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Miscellaneous transport and binding events
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Cancer ( 29299148) Dermatomyositis ( 27153935)
Interacting Genes		14 interacting genes: AKR1B1 CD247 EIF3H FCGR2B GLI4 GML GPAA1 HSF1 JRK MFSD6 PIP TMEM140 TMEM19 TRARG1	5 interacting genes: CD4 LY6E NEIL3 SPI1 USP7
Entrez ID		4061	5304
HPRD ID		03227	07179
Ensembl ID		ENSG00000160932	ENSG00000159763
Uniprot IDs		Q16553	P12273
PDB IDs			3ES6
Enriched GO Terms of Interacting Partners?		IgG Binding	Regulation Of Myeloid Cell Differentiation Response To Ethanol Macrophage Differentiation Immunoglobulin Binding Response To Methamphetamine Hydrochloride MHC Class II Protein Binding Response To Stress Interleukin-16 Binding Positive Regulation Of Leukocyte Differentiation Lymphocyte Differentiation Interleukin-16 Receptor Activity Cellular Response To Ionomycin Myeloid Cell Differentiation Helper T Cell Enhancement Of Adaptive Immune Response Myeloid Leukocyte Differentiation Acetylcholine Receptor Inhibitor Activity Regulation Of Myeloid Progenitor Cell Differentiation Regulation Of Neutrophil Degranulation Positive Regulation Of Microglial Cell Mediated Cytotoxicity Pericyte Cell Differentiation Endothelial To Hematopoietic Transition Positive Regulation Of Myeloid Dendritic Cell Chemotaxis Apoptotic Process Involved In Blood Vessel Morphogenesis Positive Regulation Of Antifungal Innate Immune Response Pro-T Cell Differentiation NFAT Protein Binding Oncogene-induced Cell Senescence Negative Regulation Of Neutrophil Degranulation Negative Regulation Of MHC Class II Biosynthetic Process Follicular B Cell Differentiation Negative Regulation Of Protein Localization To Chromatin Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Retrograde Transport, Endosome To Golgi Class I DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Depurination MCM Complex Binding Hydrolase Activity, Hydrolyzing N-glycosyl Compounds Response To Alcohol Delamination Negative Regulation Of Adipose Tissue Development Bubble DNA Binding Regulation Of Protein Localization To Chromatin TRAIL-activated Apoptotic Signaling Pathway Germinal Center B Cell Differentiation Epigenetic Regulation Of Gene Expression Monoubiquitinated Protein Deubiquitination Cellular Response To Ether Interleukin-15-mediated Signaling Pathway
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