ID3 and CEP350

		ID3	CEP350
Description		inhibitor of DNA binding 3	centrosomal protein 350
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Spindle Cytosol Cytoskeleton Membrane Ciliary Basal Body Cell Projection
	Molecular Function	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding BHLH Transcription Factor Binding Protein Dimerization Activity Transcription Regulator Inhibitor Activity Leptomycin B Binding	Protein Binding Microtubule Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Regulation Of DNA Replication Central Nervous System Development Heart Development Muscle Organ Development Circadian Rhythm Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Neuron Differentiation Epithelial Cell Differentiation Notochord Development Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Leptomycin B	Microtubule Anchoring Protein Localization To Centrosome Non-motile Cilium Assembly
Pathways		NGF-stimulated transcription
Drugs
Diseases
GWAS			Anorexia nervosa ( 23568457) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Smoking initiation ( 30617275)
Interacting Genes		50 interacting genes: ADD1 ANKS1A ATF3 BOLA2 BOLA2B C22orf39 CBFA2T2 CDK2 CEP350 CNOT3 CREB5 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 FRS3 GATA4 GNB2 GTF2A1L GUCD1 HES1 HOXA1 ID4 IFI16 IKBKG KAT5 KRTAP26-1 LMO4 MLX MSGN1 MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SDCBP SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626	11 interacting genes: ADIPOR1 APH1A APP APTX ID3 NR1H3 PLEKHA5 PPARA PPARD PPARG RSRP1
Entrez ID		3399	9857
HPRD ID		02608	09870
Ensembl ID		ENSG00000117318	ENSG00000135837
Uniprot IDs		Q02535	Q5T2X4 Q5VT06
PDB IDs		2LFH	2COZ
Enriched GO Terms of Interacting Partners?		Protein Dimerization Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding E-box Binding Chromatin RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Cellular Developmental Process Nucleus Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Cell Differentiation Negative Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Skeletal Muscle Cell Differentiation Negative Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Skeletal Muscle Fiber Development Nucleoplasm Positive Regulation Of Metabolic Process Transcription Regulator Complex Cell Fate Commitment Negative Regulation Of Macromolecule Biosynthetic Process Muscle Cell Fate Commitment Positive Regulation Of Macromolecule Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Biosynthetic Process Positive Regulation Of Myoblast Differentiation Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Striated Muscle Tissue Development	Negative Regulation Of Cholesterol Storage Negative Regulation Of Lipid Storage Negative Regulation Of MiRNA Transcription Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Small Molecule Metabolic Process Hormone-mediated Signaling Pathway Regulation Of Lipid Storage Nuclear Receptor Activity Positive Regulation Of Small Molecule Metabolic Process Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Regulation Of Fatty Acid Metabolic Process Regulation Of Lipid Metabolic Process Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Ketone Metabolic Process RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Lipid Metabolic Process Negative Regulation Of Cell Differentiation Regulation Of Inflammatory Response Negative Regulation Of Inflammatory Response Cellular Response To Oxygen-containing Compound Negative Regulation Of Type II Interferon-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Negative Regulation Of Developmental Process Regulation Of Cell Differentiation Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Defense Response Peroxisome Proliferator Activated Receptor Signaling Pathway Fatty Acid Metabolic Process Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon Nuclear Receptor-mediated Signaling Pathway Positive Regulation Of Fatty Acid Oxidation Regulation Of Circadian Rhythm Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Lipid Transport Nuclear Steroid Receptor Activity Regulation Of Defense Response Negative Regulation Of RNA Metabolic Process Response To Nutrient Regulation Of Protein Transport Positive Regulation Of Cholesterol Efflux Negative Regulation Of Myoblast Differentiation Negative Regulation Of Receptor Signaling Pathway Via STAT Negative Regulation Of Cell Growth Sequence-specific DNA Binding Monocarboxylic Acid Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process
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