NDST1 and ABLIM3

		NDST1	ABLIM3
Description		N-deacetylase and N-sulfotransferase 1	actin binding LIM protein family member 3
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Trans-Golgi Network Membrane	Stress Fiber Cytoplasm Actin Cytoskeleton Lamellipodium Synapse Glutamatergic Synapse
	Molecular Function	Catalytic Activity Protein Binding Sulfotransferase Activity Heparan Sulfate N-sulfotransferase Activity Transferase Activity Hydrolase Activity Deacetylase Activity N-acetylglucosamine Deacetylase Activity Heparan Sulfate N-deacetylase Activity	Actin Binding Protein Binding Metal Ion Binding Actin Filament Binding
	Biological Process	Polysaccharide Biosynthetic Process Cardiac Septum Development Inflammatory Response Heart Development Respiratory Gaseous Exchange By Respiratory System Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Animal Organ Morphogenesis Heparan Sulfate Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Heparin Proteoglycan Biosynthetic Process Forebrain Development Midbrain Development Aorta Development Positive Regulation Of MAPK Cascade Positive Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Embryonic Viscerocranium Morphogenesis Coronary Vasculature Development	Transcription By RNA Polymerase II Cytoskeleton Organization Lamellipodium Assembly Positive Regulation Of Transcription By RNA Polymerase II Cilium Assembly Positive Regulation Of Protein Targeting To Mitochondrion
Pathways		HS-GAG biosynthesis	DCC mediated attractive signaling
Drugs		Adenosine 3',5'-diphosphate
Diseases
GWAS		Appendicular lean mass ( 33097823) Blood protein levels ( 30072576) Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Neutrophil count ( 32888494)	Age-related hearing impairment ( 34108613) Body mass index ( 25673413) Chronic obstructive pulmonary disease ( 30804561) Diastolic blood pressure ( 26390057 28739976) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163) FEV1 ( 30804560) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Macular thickness ( 30535121) Peak expiratory flow ( 30804560)
Interacting Genes		2 interacting genes: LCOR RUNX1	14 interacting genes: ABI2 ACTC1 BANP CATSPER1 CBX8 CCDC33 CWF19L2 HIKESHI IKZF3 PALMD SNW1 SSX2IP TFIP11 ZNF620
Entrez ID		3340	22885
HPRD ID		02912	12411
Ensembl ID		ENSG00000070614	ENSG00000173210
Uniprot IDs		A8K8T3 P52848	A0A0C4DGA7 O94929
PDB IDs		1NST 8CCY 8CD0 8CHS	1UJS 2DJ7
Enriched GO Terms of Interacting Partners?
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