NDST1 and SYNPO

		NDST1	SYNPO
Description		N-deacetylase and N-sulfotransferase 1	synaptopodin
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Trans-Golgi Network Membrane	Stress Fiber Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Bicellular Tight Junction Postsynaptic Density Actin Cytoskeleton Z Disc Cell Projection Dendritic Spine Perikaryon Organelle Synapse Anchoring Junction Spine Apparatus Glutamatergic Synapse
	Molecular Function	Catalytic Activity Protein Binding Sulfotransferase Activity Heparan Sulfate N-sulfotransferase Activity Transferase Activity Hydrolase Activity Deacetylase Activity N-acetylglucosamine Deacetylase Activity Heparan Sulfate N-deacetylase Activity	Actin Binding Protein Binding
	Biological Process	Polysaccharide Biosynthetic Process Cardiac Septum Development Inflammatory Response Heart Development Respiratory Gaseous Exchange By Respiratory System Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Animal Organ Morphogenesis Heparan Sulfate Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Heparin Proteoglycan Biosynthetic Process Forebrain Development Midbrain Development Aorta Development Positive Regulation Of MAPK Cascade Positive Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Embryonic Viscerocranium Morphogenesis Coronary Vasculature Development	Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Stress Fiber Assembly Spine Apparatus Assembly
Pathways		HS-GAG biosynthesis
Drugs		Adenosine 3',5'-diphosphate
Diseases
GWAS		Appendicular lean mass ( 33097823) Blood protein levels ( 30072576) Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Neutrophil count ( 32888494)	Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401)
Interacting Genes		9 interacting genes: ABLIM3 ADAM18 CAMK2A HMGXB3 ITGA11 LCOR RUNX1 ST6GALNAC1 SYNPO	11 interacting genes: CDC5L G3BP1 MAGI1 NCK1 NCK2 NDST1 NONO NUFIP2 SGF29 YWHAG YWHAZ
Entrez ID		3340	11346
HPRD ID		02912	12179
Ensembl ID		ENSG00000070614	ENSG00000171992
Uniprot IDs		A8K8T3 P52848	Q8N3V7
PDB IDs		1NST 8CCY 8CD0 8CHS
Enriched GO Terms of Interacting Partners?			Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Protein Sequestering Activity Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Protein Domain Specific Binding Response To Stress Positive Regulation Of Translation In Response To Stress Receptor Tyrosine Kinase Binding Signal Complex Assembly Cellular Response To Stress Regulation Of Translation In Response To Endoplasmic Reticulum Stress Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Translational Initiation Positive Regulation Of Cell-cell Adhesion Regulation Of PERK-mediated Unfolded Protein Response Negative Regulation Of Intracellular Signal Transduction Cytoskeletal Anchor Activity Regulation Of Translation In Response To Stress Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Signal Transduction Positive Regulation Of Translation Negative Regulation Of Cell Communication Negative Regulation Of Signaling RNA Binding Signaling Receptor Complex Adaptor Activity Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Regulation Of Intrinsic Apoptotic Signaling Pathway Lamellipodium Assembly Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response Vesicle Membrane Positive Regulation Of Response To Endoplasmic Reticulum Stress Lamellipodium Organization Response To Endoplasmic Reticulum Stress Positive Regulation Of Translational Initiation Positive Regulation Of Actin Filament Polymerization Molecular Condensate Scaffold Activity Cellular Response To Glucose Starvation Negative Regulation Of Response To Endoplasmic Reticulum Stress Ephrin Receptor Signaling Pathway Innate Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Gene Expression Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Intracellular Signal Transduction Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?