LMOD1 and IQCB1

		LMOD1	IQCB1
Description		leiomodin 1	IQ motif containing B1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Striated Muscle Thin Filament Actin Filament Membrane Myofibril Sarcomere	Photoreceptor Outer Segment Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Photoreceptor Connecting Cilium Extracellular Exosome
	Molecular Function	Actin Binding Tropomyosin Binding	Protein Binding Calmodulin Binding Enzyme Binding Protein-macromolecule Adaptor Activity BBSome Binding
	Biological Process	Muscle Contraction Actin Filament Organization Myofibril Assembly Positive Regulation Of Actin Filament Polymerization Actin Nucleation Pointed-end Actin Filament Capping	Cell Projection Organization Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Cilium Assembly Cytosolic Ciliogenesis
Pathways		Smooth Muscle Contraction	Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Senior-Loken syndrome
GWAS		Appendicular lean mass ( 33097823) Body mass index ( 28448500 28892062 29273807) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Breast size ( 27182965) Coronary artery disease ( 29212778 33020668) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Lung function (FEV1/FVC) ( 30804560) Sleep duration (short sleep) ( 30846698)	Hemoglobin levels ( 32327693) Multiple sclerosis ( 24076602 31604244) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376)
Interacting Genes		2 interacting genes: ACTB IQCB1	18 interacting genes: CALM2 CALML3 CD80 KIF9 LDOC1 LMOD1 MARCHF7 MNS1 NECTIN3 PCMT1 PDE9A SESTD1 SMARCD1 SPG21 TBL1X TRH TRIM32 UPK1B
Entrez ID		25802	9657
HPRD ID		04093	11049
Ensembl ID		ENSG00000163431	ENSG00000173226
Uniprot IDs		P29536	Q15051
PDB IDs		4Z79 4Z8G 4Z94
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Regulation Of Norepinephrine Uptake BBSome Binding Regulation Of Transepithelial Transport Protein Localization To Adherens Junction Dense Body Transporter Regulator Activity Morphogenesis Of A Polarized Epithelium Maintenance Of Animal Organ Identity Cytosolic Ciliogenesis Structural Constituent Of Postsynaptic Actin Cytoskeleton Nitric-oxide Synthase Regulator Activity BBAF Complex Tat Protein Binding Postsynaptic Actin Cytoskeleton Brahma Complex Nitric-oxide Synthase Binding NBAF Complex Apical Protein Localization RSC-type Complex Adherens Junction Assembly Negative Regulation Of Cell Differentiation Postsynaptic Actin Cytoskeleton Organization NpBAF Complex GBAF Complex Protein Localization To Cell-cell Junction Calyx Of Held Postsynaptic Cytoskeleton Organization Regulation Of Synaptic Vesicle Endocytosis Regulation Of Nucleotide-excision Repair Negative Regulation Of Developmental Process Apical Junction Complex Cortical Cytoskeleton NuA4 Histone Acetyltransferase Complex Regulation Of Synaptic Vesicle Recycling SWI/SNF Complex Maintenance Of Blood-brain Barrier Cell Projection Organization Regulation Of G0 To G1 Transition Tight Junction Nucleosomal DNA Binding Photoreceptor Cell Maintenance Kinesin Binding Substantia Nigra Development Tau Protein Binding Photoreceptor Connecting Cilium Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Myoblast Differentiation Platelet Aggregation	Detection Of Calcium Ion Regulation Of Cilium Assembly Regulation Of Organelle Assembly Calcium Channel Complex Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Calcium Ion Transmembrane Transport Calcineurin-mediated Signaling Myelin Sheath Negative Regulation Of Cell Population Proliferation Regulation Of Organelle Organization Thyrotropin-releasing Hormone Activity Positive Regulation Of Interleukin-17-mediated Signaling Pathway Negative Regulation Of Cilium Assembly Actin Ubiquitination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production
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