ERP44 and PPP3R2

		ERP44	PPP3R2
Description		endoplasmic reticulum protein 44	protein phosphatase 3 regulatory subunit B, beta
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cell Surface Specific Granule Lumen Extracellular Exosome	Mitochondrion Cytosol Calcineurin Complex Protein Serine/threonine Phosphatase Complex Sperm Flagellum Sperm Midpiece Sperm Mitochondrial Sheath
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding	Calcium Ion Binding Protein Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Phosphatase Binding Metal Ion Binding
	Biological Process	Protein Folding Response To Unfolded Protein Glycoprotein Metabolic Process Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis	Penetration Of Zona Pellucida Positive Regulation Of Calcineurin-NFAT Signaling Cascade Calcineurin-mediated Signaling Positive Regulation Of Calcium Ion Import Across Plasma Membrane Negative Regulation Of Calcium Ion Import Across Plasma Membrane
Pathways		Neutrophil degranulation
Drugs			Cyclosporine Voclosporin
Diseases
GWAS		Preeclampsia ( 23551011)
Interacting Genes		12 interacting genes: ABCA1 CYLC2 ERO1A ERO1B ITPR1 MRPL50 NIPSNAP3A PLPPR1 PPP3R2 SMC2 STX17 TEX10	19 interacting genes: APC AURKA BUB1 CCND1 CD14 DLC1 DYNLL1 ERP44 FBXW7 KRT34 MLH3 MSH2 PDGFRL PTPN12 PTPRJ RAB32 SMAD4 TBC1D10C TFCP2
Entrez ID		23071	5535
HPRD ID		10290	10164
Ensembl ID		ENSG00000023318	ENSG00000188386
Uniprot IDs		A0A384MEE7 Q9BS26	Q96LZ3
PDB IDs		2R2J 5GU6 5GU7 5HQP 5XWM
Enriched GO Terms of Interacting Partners?		Calcineurin Complex Thiol Oxidase Activity Protein Folding In Endoplasmic Reticulum Protein-disulfide Reductase Activity Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis FAD Binding Endoplasmic Reticulum Membrane Sphingolipid Floppase Activity Release Of Sequestered Calcium Ion Into Cytosol Inositol 1,4,5-trisphosphate Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Levels Negative Regulation Of Sequestering Of Calcium Ion Response To Vitamin B3 Positive Regulation Of High-density Lipoprotein Particle Assembly Apolipoprotein A-I Receptor Activity Cytoskeletal Calyx Endoplasmic Reticulum-Golgi Intermediate Compartment Organization	Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Centromeric DNA Binding Kinetochore Negative Regulation Of Mitotic Cell Cycle Gamma-catenin Binding Mismatched DNA Binding Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway DNA Damage Response Ruffle Membrane ATP-dependent DNA Damage Sensor Activity Negative Regulation Of Cell Cycle Process Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Signal Transduction Regulation Of Programmed Cell Death Negative Regulation Of Cytoskeleton Organization Regulation Of Apoptotic Process Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Supramolecular Fiber Organization Protein-containing Complex Binding Negative Regulation Of Phosphate Metabolic Process Response To Stress Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Cycle Negative Regulation Of Cell Communication Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Nuclear Division Regulation Of Mitotic Nuclear Division Regulation Of Cell Cycle Negative Regulation Of Signaling Negative Regulation Of Phosphorylation Mitotic Cell Cycle Phase Transition Liver Regeneration Response To UV Response To X-ray Cell Cycle Phase Transition Regeneration Organelle Organization Chromosome Organization Mismatch Repair Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
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