SEC16A

Description		SEC16 homolog A, endoplasmic reticulum export factor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol ER To Golgi Transport Vesicle Membrane Membrane Organelle Membrane Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding
	Biological Process	Regulation Of COPII Vesicle Coating Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Endoplasmic Reticulum Organization Golgi Organization Intracellular Protein Localization Protein Transport Vesicle-mediated Transport Substantia Nigra Development Protein Exit From Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Protein Stabilization Localization Within Membrane Protein Localization To Endoplasmic Reticulum Exit Site Protein Localization To Plasma Membrane
Pathways		COPII-mediated vesicle transport
Drugs
Diseases
GWAS		Basal cell carcinoma ( 31174203) Crohn's disease ( 28067908) Cutaneous squamous cell carcinoma ( 27424798 32041948) Eosinophil count ( 27863252) Femur bone mineral density x serum urate levels interaction ( 34046847) Height ( 28552196) Inflammatory bowel disease ( 28067908) Monocyte percentage of white cells ( 32888494) Serum alkaline phosphatase levels ( 33547301) Squamous cell carcinoma ( 31174203) Triglyceride levels ( 32154731) Ulcerative colitis ( 21297633 28067908)
Novel Interacting Genes		2 novel interacting genes: MIA3 SEC23A
Interacting Genes		2 interacting genes: MIA3 SEC23A
Entrez ID		9919
HPRD ID		11075
Ensembl ID		ENSG00000148396
Uniprot IDs		A0A8I5KPG1 F1T0I1 O15027
PDB IDs
Enriched GO Terms of Interacting Partners?		COPII-coated Vesicle Cargo Loading Vesicle Cargo Loading Endoplasmic Reticulum Exit Site Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Vesicle Transport COPII-coated Vesicle Budding Protein Localization To Endoplasmic Reticulum Exit Site COPII Vesicle Coat Lipoprotein Transport Negative Regulation Of Lymphocyte Migration Protein Localization To Endoplasmic Reticulum Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Vesicle Budding From Membrane Endoplasmic Reticulum Membrane Vesicle-mediated Transport COPII-coated ER To Golgi Transport Vesicle Intracellular Transport Protein Transport Cellular Response To Lipoprotein Particle Stimulus Cargo Receptor Activity Blood Vessel Endothelial Cell Migration Cellular Response To Low-density Lipoprotein Particle Stimulus Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Mononuclear Cell Migration Establishment Of Protein Localization Cellular Localization ER To Golgi Transport Vesicle Membrane Endoplasmic Reticulum Establishment Of Localization In Cell Endoplasmic Reticulum Organization Regulation Of Lymphocyte Migration Negative Regulation Of Leukocyte Migration Wound Healing Endothelial Cell Migration Intracellular Protein Localization Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Negative Regulation Of Leukocyte Cell-cell Adhesion
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