SRGAP3

Description		SLIT-ROBO Rho GTPase activating protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Synapse Postsynapse
	Molecular Function	GTPase Activator Activity Protein Binding
	Biological Process	Signal Transduction Nervous System Development Negative Regulation Of Cell Migration Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Synapse Assembly
Pathways		Inactivation of CDC42 and RAC1 CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Body fat percentage ( 31752434) Lead levels in blood ( 25820613) Rapid automised naming of letters ( 30741946)
Novel Interacting Genes		11 novel interacting genes: DISC1 DTNBP1 ENKD1 FASLG KDM1A PRMT6 RAC1 SMARCC2 SUV39H1 TNIK WASF1
Interacting Genes		11 interacting genes: DISC1 DTNBP1 ENKD1 FASLG KDM1A PRMT6 RAC1 SMARCC2 SUV39H1 TNIK WASF1
Entrez ID		9901
HPRD ID		12108
Ensembl ID		ENSG00000196220
Uniprot IDs		O43295
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Regulation Of Developmental Process Regulation Of Dendritic Spine Development Cytoskeleton Organization Cell Projection Morphogenesis Cell Projection Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Cell Projection Organization Actin Cytoskeleton Organization Cell Projection Assembly Cerebral Cortex Radially Oriented Cell Migration Regulation Of Signal Transduction Regulation Of Anatomical Structure Morphogenesis Regulation Of Multicellular Organismal Development Rac Protein Signal Transduction Regulation Of Cell Development Actin Filament-based Process Regulation Of Postsynapse Organization Histone H3 Methyltransferase Activity Regulation Of Neuron Projection Development Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Neuroblast Proliferation Cerebral Cortex Cell Migration Actin Filament Polymerization Histone Methyltransferase Activity Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Cell Communication Positive Regulation Of Signaling Telencephalon Cell Migration Lamellipodium Organization Glutamatergic Synapse Regulation Of DNA Repair Regulation Of Neuroblast Proliferation Ciliary Base Forebrain Cell Migration Dendrite Morphogenesis Developmental Process Positive Regulation Of Neural Precursor Cell Proliferation Non-motile Cilium Assembly Cilium Assembly Neuron Projection Morphogenesis Chromatin Remodeling Establishment Of Organelle Localization Wnt Signaling Pathway Actin Polymerization Or Depolymerization Histone H2AR3 Methyltransferase Activity
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